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頁籤選單縮合
題 名 | Intellectual Outcomes of Patients with Congenital Hypothyroidism Not Detected by Neonatal Screening=非新生兒篩檢發現的先天性甲狀腺低能症患者的智力預後 |
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作 者 | 蕭佩宏; 丘彥南; 蔡文友; 蘇淑貞; 李俊賢; 宋維村; | 書刊名 | 臺灣醫學會雜誌 |
卷 期 | 98:7 1999.07[民88.07] |
頁 次 | 頁512-515 |
分類號 | 415.931 |
關鍵詞 | 非新生兒篩檢; 先天性甲狀腺低能症; 智力; Congenital hypothyroidism; Intelligence quotient; |
語 文 | 英文(English) |
英文摘要 | Mental retardation is a major sequela of delayed treatment of congenital hypothyroidism. In this study, we investigated the intellectual outcomes of patients with congenital hypothyroidism diagnosed before a nationwide screening project started. Eighty-two patients had intelligence tests done while in the euthyroid state. Their mean intelligence quotient (IQ) was 78±21 (± SD) (n=79). The mean verbal IQ was significantly higher than the mean full-scale IQ. The mean lQs of both ectopic thyroid 84±21, n=28) and dyshormonogenic patients (85±14, n=18) were significantly higher than that of patients with athyrosis (64±18, n=19) (p < 0.05). Patients who were treated before 3 months of age had significantly higher mean IQs (90±16, n=16) than those treated after 3 months (75±21, n=63) (p < 0.01). Our results confirm that both patients with ectopic thyroids and those with dyshormonogenesis have better intellectual outcomes than athyrotic patients do, and that early treatment Improves the intellectual outcome of patients with congenital hypothyroidism. |
本系統中英文摘要資訊取自各篇刊載內容。