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頁籤選單縮合
題名 | 利用超音波技術來評估骨質疏鬆症=Evaluation of Osteoporosis by Ultrasonic Techniques |
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作者 | 方昶翔; 陳培展; 陳天送; 林啟禎; | 書刊名 | 中華醫學工程學刊 |
卷期 | 19:1 1999.03[民88.03] |
頁次 | 頁67-74 |
分類號 | 416.13 |
關鍵詞 | 骨質疏鬆症; 超音波; Osteoporosis; Ultrasound; |
語文 | 中文(Chinese) |
中文摘要 | 骨質疏鬆症會導致骨質流失,而骨質的流失又是造成骨折的重大因素,所以骨質 疏鬆症已視為全世界一個健康的主要課題。因此如何能早期預防與早期治療就顯得非常重要 。一般診斷骨質疏鬆症的方法,主要是測量骨質密度 (BMD),如雙能量 X 光吸收計 (DEXA) 及量化的電腦斷層掃描 (QCT)。由於這些方法均伴隨著游離輻射,所以病人可能會受到輻射 的危險。相較於這些具有游離電磁波輻射的吸收計,超音波的量測近來已顯示可當作一種非 侵入式的技術來測量骨骼的強度及預測骨折的發生率。超音波是一種機械波,因此對於骨骼 不會有游離的危險,所以超音波被視為一種相當具有潛力評估骨質狀況的方式。 本文應用已發展的雙探頭超音波技術,其原理是利用雙探頭反射模式來量測骨骼中超音 波的傳遞速度。其方法是將兩個換能器放置在同一邊,一個當發射及接收訊號,而另一個只 負責接收訊號。從這些回波訊號及兩換能器之間的距離,代入所推導的公式中即可求得超音 波在骨骼中傳遞的速度,而不須事先知道骨骼的厚度,使得臨床的實用性大增。 利用本系統為23位門診病患作量測,而這23位病患也同時作DE絀的量測。結果顯示,本 系統所測得的聲速值與 D 口仇所測得的骨質密度值, 兩者之間的相關係數值約為 0.8856。 由於兩者之間的相關係數值高,所以本系統是一種很準確的量測方式,患者可以不用受到輻 射的傷害,就可以知道骨質的大約狀況。 |
英文摘要 | Osteoporosis is one of the major health problems in the world. The disease leading the loss in bone minerial is one of the risk factors for fracture. Thus, how to prevent and to cure the osteoporosis in advance is very important. Commonly used methods of diagnosing osteoporosis, such as dual-energy X-ray absoroptiometry (DEXA) and quantitative computed tomgraphy, measure the quantitative aspect of bone mineral density(BMD). Because these methods are associated with ionizing radiation, patients are more likely in danger of being exposed to the X-ray. In contrast with the ionizing electromagnetic radiation of such clinical bone densitometric techniques, ultrasonic measurement of bone has recently emerged as a promising noninvasive technology for measurement of bone strength and fracture risk. Ultrasound is a mechanical wave and thus interacts with bone in a fundamentally distinct manner, so ultrasound is viewed as having great potential for assessing bone. In this paper, a new dual ultrasonic technique was employed to measure the velocity of ultrasound waves transmitted through the bone. This technique utilizes dual transducer reflected ultrasound to measure acoustic speed of bone tissue, where two transducer were placed on the same side of the test object; one for the transmitter and receiver, and the other one for the receiver only. The acoustic speed of bone tissue can be easily obtained from the information of time-of-flights on both transducers and the separation distance of these two transducers without the knowledge of bone thickness which is difficult to measure in biological tissue. Therefore, this technique makes the clinical applications possible. Twenty-three patients were tested in this study who also had their bone mineral density measured by DEXA. The results showed that the correlation between the sound speed measured by the system and the bone mineral density measured by DEXA was 0.8856. With high correlation of these two systems, it is a precise method of assessing bone status without exposing the patient to sources of radiation. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。