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| 題 名 | Small Cell Lung Carcinoma Associated with Paraneoplastic Limbic Encephalitis=肺小細胞癌併副癌性邊緣腦炎 |
|---|---|
| 作 者 | 許健威; 王鴻昌; 盧朝勇; | 書刊名 | 臺灣醫學會雜誌 |
| 卷 期 | 98:5 1999.05[民88.05] |
| 頁 次 | 頁368-371 |
| 分類號 | 415.468 |
| 關鍵詞 | 肺小細胞癌; 副癌性邊緣腦炎; Limbic encephalitis; Paraneoplastic syndrome; Small cell lung carcinoma; |
| 語 文 | 英文(English) |
| 英文摘要 | Limbic encephalitis is an unusual presentation of paraneoplastic syndrome. We report a case of small cell lung carcinoma associated with limbic encephalitis. A 67-year-old man presented with convulsions, memory impairment, and neuro- psychiatric disturbances as initial symptoms. Subsequently, small cell lung carcinoma was diagnosed by bronchoscopic biopsy. The cerebrospinal fluid studies, electroencephalography, and magnetic resonance imaging findings had distinctive features compatible with paraneoplastic limbic encephalitis. The neuro-psychiatric symptoms improved significantly after six cycles of systemic chemotherapy and adjuvant radiotherapy, resulting in partial remission of the tumor. A follow-up computed tomography scan of the head showed no evidence of intracranial metastasis 7 months after the diagnosis of cancer. Limbic encephalitis may be an initial manifestation of lung cancer. Greater awareness for diagnosis and early treatment of the primary tumor offers the best chance for improvement in patients with lung cancer presenting with limbic encephalitis. |
本系統中英文摘要資訊取自各篇刊載內容。