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題名 | Acinetobacter Meningitis: Four Nosocomial Cases=不動桿菌性腦膜炎:院內感染四病例報告 |
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作者 | 張文能; 莊曜聰; 盧成獻; | 書刊名 | 臺灣醫學會雜誌 |
卷期 | 98:3 1999.03[民88.03] |
頁次 | 頁214-217 |
分類號 | 415.9313 |
關鍵詞 | 不動桿菌性腦膜炎; Acinetobacter meningitis; Imipenem/cilastatin; Multiantibiotic resistance; |
語文 | 英文(English) |
英文摘要 | We report the clinical features and therapeutic outcomes of four patients with multiantibiotic-resistant Acinetobacter meningitis. There were three males and one female, aged from 17 to 49 years. Three of them had suffered from head injuries with skull fractures, and the other suffered from an intracerebral hemorrhage and underwent a craniotomy. All four patients acquired nosocomial Acinetobacter meningitis, and multiantibiotic resistance developed. After treatment with imipenem/ cilastatin, three of the four patients survived; one died of multiorgan failure. Because the clinical manifestations of Acinetobacter meningitis are similar to those of other gram-negative bacillary meningitis, the diagnosis can only be confirmed by bacterial culture. Resistance to multiple antibiotics, including third-generation cephalosporins, is frequently seen in patients with nosocomial Acinetobacter meningitis, and imipenem/cilastatin seems to be the antibiotic of choice for this potentially fatal central nervous system infection. |
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