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題 名 | Treatment of Ultra-High Risk Gestational Trophoblastic Disease by an EMA/CE Regimen=以EMA/CE 藥方來治療超高危險滋養層疾病 |
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作 者 | 李耀泰; 尹長生; 徐文成; 許國邦; 詹景全; | 書刊名 | 中華民國婦產科醫學會會刊雜誌 |
卷 期 | 38:1 1999.03[民88.03] |
頁 次 | 頁25-29 |
分類號 | 417.1 |
關鍵詞 | 滋養層疾病; 腦轉移; 化學治療; Trophoblastic disease; Brain metastasis; Chemotherapy; |
語 文 | 英文(English) |
中文摘要 | 背景:探討以 EMA/CE 之化學冶療公式, 來治療超高危險群之滋養層疾病患者之 效果。病例報告:一 50 歲婦女,七個月前因葡萄胎而切除子宮,但手術後沒有追蹤。患者 後來因有半身輕癱、頭痛、嘔吐和視力模糊, 經檢查發現有腦轉移病灶之滋養層疾病, 其 WHO 之分數為 16。經過 6 週期的 EMA/CE 的治療,但沒有接受全腦放射治療和脊髓腔內化 學治療,患者完全康復。在 60 個月後的追蹤,並無後遺症。結論:為了避免全腦放射治療 和脊髓腔內化學治療的副作用, EMA/CE 化學冶療可能對腦轉移的超高危險滋養層患者,有 不錯之效果。 |
英文摘要 | Background: To test the efficacy of the etoposide, methotrexate and actinomycin D / cisplatin and etoposide (EMA/CE) regimen in the treatment of ultra-high risk gestational trophoblastic disease. Case report: A 50-year-old woman was admitted for trophoblastic disease complicated by brain metastasis. She was considered to be at ultra-high risk, with a WHO score of 16. After the administration of 6 courses of the EMA/CE regimen, she responded very well, and had a 60-month sustained remission without any sequalae. Conclusion: In order to avoid sequalae from whole brain radiation or intrathecal methotrexate in- jection, and to increase the cure rate, EMA/CE may be an effective alternative for patients with ultra-high risk gestational trophoblastic disease with brain ipyolvement. |
本系統中英文摘要資訊取自各篇刊載內容。