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頁籤選單縮合
題名 | 老年性黃斑部病變之境界不明脈絡膜新生血管的灌流變化=Filling Pattern of Occult Choroidal Neovascularization in Age-Related Macular Degeneration |
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作者 | 陳世真; 李鳳利; 楊昌叔; 林伯剛; 李安斐; 劉榮宏; | 書刊名 | 中華民國眼科醫學會雜誌 |
卷期 | 38:1 1999.03[民88.03] |
頁次 | 頁26-32 |
分類號 | 416.746 |
關鍵詞 | 老年性黃斑部病變; 脈絡膜新生血管; 灌流變化; 循血綠血管攝影; 雷射治療; Occult choroidal neovascularization; Filling pattern; Indocyanine green angiography; Scanning laser ophthalmoscope; |
語文 | 中文(Chinese) |
中文摘要 | 目的:觀察記錄早期脈絡膜新生血管的灌流變化,希有助於對老年性黃斑部病變 之境界不明新生血管的了解。 方法: 總共收集 37 個黃斑部病變病患, 39 隻眼,其中 18 眼為單純境界不明新生血管,12 眼為合併色素上皮細胞層剝離者。 施行循血綠血管攝影檢 查,以掃描式雷射眼底攝影取得早期新生血管的灌流變化,以及晚期的螢光反應,並加以比 較分類。結果: 很早期的新生血管灌流型態,可分為血管網狀型 (vascular net filling)? 佔 38.5%,局部滲出型 (focal oozing), 佔 62%, 以及境界不明型 (ill-defined), 佔 38%。 同一隻眼有兩種不同型態變化的佔 41%。若與晚期螢光反應做比較,早期局部滲出型 的有 83% 到晚期呈境界分明的高螢光區; 而 87% 的早期境界不明型到了晚期仍然境界不明 。兩者有統計學上差異 (P<0.001, Fisher's exactt test)。血管網狀型到晚期則各有 53% 和 47% 分呈境界分明和境界不明的高螢光區。 結論: 本研究顯示,早期脈絡膜新生血管的 循血綠灌流變化表現,與新生血管的類別和晚期螢光反應有關,這些分類可增加雷射治療的 適應症。 |
英文摘要 | Purpose: To study the early filling patterns of occult choroidal neovascularization (OCNV) in agerelated rnacular degeneration with indocyanine green angiography (ICGA) imaged by scanning laser ophthalmoscope. Methods: Total 39 eyes of OCNV were enrolled. Among them, 18 eyes were isolated OCNV and 21 eyes were OCNV with pigment epithelial detachment (vascular PED). All eyes had indocyanine green angiography imaged by scanning laser ophthalmoscope. Results: Three types of filling patterns could be identified according to the early angiographic findings. The vascular net filling accounted for 38.5%, the focal oozing for 62% and the ill-defined pattern for 38%. Forty-one percent of the eyes had two types of filling. In the late phase of angiography, 83% of the early focal oozing spots showed well-defined hyperfluorescent patches, while 87% of the early illdefined zones continued to be ill-defined in the late phase. The difference is significant (p<0.001. Fisher's exact test). Fifty-three percent and 47% of the early vascular net filling types changed to well-defined and ill-defined plaques, respectively. Conclusions: The early filling patterns of OCNV in age-related macular degeneration are related to the types of OCNV and the late phase fluorescent findings. These classifications of the early ICGA may supplement the guidelines for laser treatment. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。