頁籤選單縮合
題名 | Clinical Experiences of Germ Cell Tumor in Cryptorchid Testis=隱睪症併發睪丸生殖細胞癌的治療經驗 |
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作者 | 郭俊逸; 黃志賢; 邱文祥; 陳光國; 張心湜; | 書刊名 | The Kaohsiung Journal of Medical Sciences |
卷期 | 15:1 1999.01[民88.01] |
頁次 | 頁32-37 |
分類號 | 416.275 |
關鍵詞 | 隱睪症併發睪丸生殖細胞癌; Cryptorchid testis; Germ cell tumor; Multidisciplinary approach; |
語文 | 英文(English) |
中文摘要 | 隱睪症是男性先天異常的疾病,也是併發睪丸腫瘤的危險因子;特別位於腹內的隱睪發生腫瘤時,與陰囊內的睪丸腫瘤有所不同,其腫瘤大小非到一定程度,不易被察覺。在本研究中,我們回溯性的分析隱睪症併發睪丸生殖細胞癌的病例,以探討其診斷、治療方法及預後。這個回溯性研究,包括1973年2月至1996年12月間,於本院診治的11例隱睪症併發睪丸生殖細胞癌的病例,其中3例的隱睪症是位於鼠蹊部,8 例是位於腹內;第I病期 4 例,第 II 病期 4 例,第III病期 3 例。追蹤期間,最短是1個月,最長是 163 個月。病患年齡,最小是 22 歲,最大是80歲 (平均是47.6歲)。其組織病理診斷為精原細胞癌9例,非精原細胞癌2例。位於鼠蹊部的睪丸精原細胞癌病例中,第I病期的3例採用睪丸切除術與放射線治療,第 III 病期的1例採用睪丸切除術與化學治療;8 例位於腹內的睪丸生殖細胞癌病例,則接受集中聯合療法,其中包括睪丸切除術,放射線治療,化學治療等,在追蹤期間,第 III 病期的 2 例死亡,目前存活 9 例,存活率是 81.8%。 |
英文摘要 | The increased risk of malignancy occurring in the cryptorchid testis is well established. In order to investigate the management and outcome of germ cell tumor in cryptorchid testis, we retrospectively reviewed the records of 11 patients with cryptorchid tumor treated at our hospital between January 1973 and December 1996. Mean patient age at diagnosis was 47.6 years (range, 22 - 80). Of these patients, 3 were found in the inguinal area and 8 in the abdomen. Six occurred in the right cryptorchid testis and 5 in the left. Four patients presented with stage I disease, 4 with stage II, and 3 with stage III. Median follow-up period was 48.0 months (range 1- 163). All 3 inguinal cryptorchid tumors and 6 of 8 abdominal cryptorchid tumors were seminoma. The remaining 2 abdominal cryptorchid tumors were nonseminomatous germ cell tumor. Of the 3 patients with inguinal cryptorchid seminomas, 2 with stage I disease were treated with prophylactic radiotherapy to nodal areas and 1 with stage III disease was treated with chemotherapy. Eight patients with abdominal cryptorchid tumors were treated with multidisciplinary approaches, including radiotherapy, cisplatin-based combination chemotherapy, and surgery. The overall survival rate for patients with inguinal and abdominal cryptorchid tumor was 81.8 %. Two patients with stage III disease died during treatment and the remaining 9 patients are still alive without evidence of disease. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。