頁籤選單縮合
題名 | A Delivery Circuit for Normothermic Reperfusion Model=用於常溫心肌缺血再灌流損害模式的灌流裝置 |
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作者 | 袁師敏; 王群; | 書刊名 | The Kaohsiung Journal of Medical Sciences |
卷期 | 15:1 1999.01[民88.01] |
頁次 | 頁8-11 |
分類號 | 415.3165 |
關鍵詞 | 常溫心肌缺血再灌流損害模式; 灌流裝置; Delivery circuit; Reperfusion injury; |
語文 | 英文(English) |
中文摘要 | 為便於在常溫缺血再灌流損害模式中投以復方人參注射劑,而建立一套簡易的灌 流裝置。此裝置主要增加一個接納復方人參注射劑的靜脈回收室。在全心心肌缺血再灌流損 害模型,灌流管路與體外循環相接,復方人參注射劑與停跳液混於回收室內,泵入上行主動 脈。就內地多數實驗室而言灌流裝置的價格是可以接受的。灌流及生物化學的監測結果適宜。 病理檢視結果示兩組的粒線體平均衰壞率具有顯著的差異(70.12±2.56% vs. 25.33±17.62%, p=0.023)。兩組均無興灌流技術有關的併發症發生。本系統可提供以恆量的動脈灌流,證實 在實驗中簡便、安全而有效。 |
英文摘要 | In order to facilitate the introduction and assessment of Injectio Radix Ginseng Compositae in normothermic reperfusion model, a simplified delivery circuit is described herein. The circuit added mainly a venous reservoir collecting Injectio Radix Ginseng Compositae with cardiopulmonary bypass. Injectio Radix Ginseng Corn positae was pumped into the ascending aorta of the animal after mixing with cardioplegia in the venous reservoir. The circuit was acceptable in terms of price by most inland medical laboratories. Perfusion as well as biochemical results monitored were satisfactory. Significant difference was noted between the average damage rates of the reperfused myocardial mitochondria in groups by ultra-structural analysis (70.12*2.56% vs. 25.33*17.62%, p= 0.023). No complications associated with perfusion technique occurred in either group. The circuit could offer a constant arterial perfusion, and was proved to be simple, safe and effective in cohort. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。