查詢結果分析
相關文獻
- The Natural Degenerative Effect of Aging on Human Aortic Apparatus--Based on Collective Echocardiographic Studies
- 臺灣地區生命表之編製--蔣氏終壽年齡區間存活成數之應用
- Age and the Prognosis of Tympanoplasty Type Ⅰ
- A Population Study of House Mice (Mus Musculus Castaneus) Inhabiting Rice Granaries in Taiwan
- 國立臺灣師範大學一年級學生健康生活狀況調查與健康危險評估實驗研究
- Effect of Cigarette Smoking and Age of Disease Onset on Decline of FEV1
- 不同年齡層對基本口味嗜好性的研究
- Junior College Students' Perception and Use of Mandarin 爽(Shuang)and Taiwanese 爽(Song)--A Case Study of TJCC
- 經濟人口統計分析
- 景文技術學院男女學生應用運動場地跑走法評測心肺耐力的研究
頁籤選單縮合
題 名 | The Natural Degenerative Effect of Aging on Human Aortic Apparatus--Based on Collective Echocardiographic Studies=年齡老化對於主動脈瓣及根部之影響--根據一系列之超音波觀察報告 |
---|---|
作 者 | 林廷燦; 郭憲文; 林世崇; 林少琳; 姜洪霆; | 書刊名 | Acta Cardiologica Sinica |
卷 期 | 14:3 民87.07-09 |
頁 次 | 頁111-119 |
分類號 | 415.384 |
關鍵詞 | 年齡; 主動脈瓣肥厚; 主動脈狹窄; 主動脈返流; 主動脈根部擴張; Aging; Thickened aortic valve; TAV; Aortic stenosis; Aortic regurgitation; Aortic root dilatation; |
語 文 | 英文(English) |
中文摘要 | 背景:年齡分佈與心血管疾病之關係乃是人們常探討之課題。年齡相關之主動脈器官之變化,先前已有文獻探討。但大型之研究仍付之闕如。因此本篇研究旨在探討國人主動脈瓣及根部變化與年齡之關係。 方法:本篇為回溯性分析。總計收集2537超音波病例來探討主動脈瓣肥厚以及年齡相關之主動脈瓣及根部退化問題。為了年齡區分方便,分成五個族群:青春組(<20歲,83例);成人組(20-39歲,270例);中年組(40-59歲,59例);老人組(60-79歲,1420例);年邁組(>80歲,172例)。 結果:整體而言,主動脈瓣肥厚發生率為18.2%在青春組為0%,成人組為1.8%。中年組為6.9%,老人組為24.1%,年邁組為43.6%。主動脈瓣肥厚主要發生於非冠狀瓣其次市是右冠狀瓣(29.6%),左側最少為(27.5%)。主動脈瓣狹窄或返流發生率隨著年齡增加而增加。根據多項變異統計回歸分析:影響主動脈根部擴張因素主要為年齡,脈瓣肥厚侵犯多寡,主動脈瓣狹窄或返流嚴重度而定。 結論:主動脈瓣狹窄主要侵犯於非冠狀動脈瓣,其發生率隨著年齡增加而成長,總之,年齡過程乃老化過程之一環,會誘發主動脈瓣肥厚,根部擴張,返流或狹窄。其年齡對於主動脈瓣病變嚴重度之進展,仍需靠前瞻性大型研究來証實。 |
英文摘要 | Background. Aging has been variously defined and investigated, many concepts regarding it have been involved. Aging-related aortic degenerative events have been noted in previous reports. But few large-scale surveys regarding this issue have been performed on Asian populations. Thus, the objective of this observational survey was to examine the concepts as they may apply here. Materials and methods. Routine echocardiography in 2537 subjects from hospital-based populations were studied to assess the incidence of thickened aortic valve as well as to clarify any changes in the aortic valve and aortic root caused by aging. Subjects were divided into five groups: adolescence (Al, <20, N=83), adulthood (Ad, 20-39, N=270), middle age (M, 40-59, N=592), elderly (E, 60-79, N=1420), and octogenarian (O, ≧80, N=172). Results. The incidence of thickened aortic valve (TAV), was found in 18.2% of the study population (Al=0%, Ad=1.8%, M=6.9%, E=24.1%, O=43.6%). Thickened aortic valve occurred with more significant frequency over the noncoronary cusp (42.9%) than the left (27.5%) or right (29.6%) cusps. The incidence and severity of aortic stenosis and aortic regurgitation also significantly increased with age. Moreover, based on multivariate analysis, age, uni- or multi-cusp involvement, severity of aortic regurgitation and aortic stenosis were important factors affecting aortic root dilation. Conclusion. TAV occurred predominantly over the noncoronary cusp as opposed to the left or right cusp. The incidence of TAV also increased with aging. In summary, the aging process is a key factor for inducing thickened aortic valve, aortic root dilatation and associated aortic pathology. However, the relevance of aging-induced progression of aortic pathology remains to be determined by a prospective cohort study. |
本系統中英文摘要資訊取自各篇刊載內容。