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題 名 | Effect of Postprepared Sperm Parameters and Insemination Specimen Volume on the Outcome of Intrauterine Insemination=精液洗滌後精蟲係數與體積對人工受精結果之影響 |
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作 者 | 蔡孟穎; 蔡永杰; 張榮州; 龔福財; 吳介甫; 黃富仁; 張旭陽; 楊寧正; | 書刊名 | 長庚醫學 |
卷 期 | 21:3 1998.09[民87.09] |
頁 次 | 頁265-270 |
分類號 | 415.87 |
關鍵詞 | 係數; 體積; 人工受精; 活動力; Parameters; Volume; Intrauterine insemination; Motility; |
語 文 | 英文(English) |
中文摘要 | 背景:本研究之目標,乃希望發現精蟲洗滌後各項係數,包含注射體積和人工受 精結果的關係。 方法:本研究是一含 306對不孕夫婦之回溯性研究。患者行人工受精時隨機地注射0.5或1.0 毫升的洗滌後精蟲,然後以卡方檢驗比較這兩組的懷孕率的優劣。另外並以多變數複迴歸方 式,取得其他各項精蟲係數和臨床結果的關係。 結果:惟一和臨床結果有相關的係數是洗滌後精蟲的活動力,其p值為0.0331。在活動力大於 95%時懷孕率達27.91%,小於75%者中則只有 2人懷孕。注射0.5毫升和1.0毫升的懷孕率分別 是12.12%及16.13%,無統計學上的差別,p值是0.427。 結論:洗滌後精蟲的活動力是惟一可以預估成功率的係數。75%的活動力可做為一篩選標準 ,以下者懷孕率極低,應考慮以其他方式治療。注射1.0毫升的洗滌後精蟲和注射0.5毫升者 其臨床結果一樣好,並無顯著差異。 |
英文摘要 | Background: The purpose of the present study was to identify the postprepared sperm parameters affecting the outcome of intrauterine insemination and to find out whether the volume of insemination specimen was a determinant factor in the rate of successful conception. Materials and Methods: A retrospective study including 306 couples was designed. The patients were inseminated with either 1.0 or 0.5 ml of prepared specimens. The pregnancy rates were compared using the chi-square test. Logistic regression was chosen for multivariant analysis of the parameters. Results: The only parameter significantly affecting the success rate was the postprepared sperm motility (p=0.033). The pregnancy rate was 27.91% in cases with≧95% sperm motility. Only two patients with less than 75% sperm motility conceived. The pregnancy rates in cases with 0.5 ml and 1.0 ml inseminations were 12.12% and 16.13%, respectively. This difference was statistically insignificant (p=0.427). Conclusion: The postprepared sperm motility was the only parameter predicting the successful rate of intrauterine insemination. Seventy-five percent sperm motility can be used as a cut-off value for selecting patients. The volume of insemination specimen did not influence the outcome, Insemination with 1 ml of fluid was just as effective as insemination with 0.5 ml. |
本系統中英文摘要資訊取自各篇刊載內容。