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題 名 | Intradermal Injection of Tramadol Has Local Anesthetic Effect: A Comparison with Lidocaine=皮內注射tramadol有局部麻醉之作用:與lidocaine之比較 |
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作 者 | 龐維伍; 莫世湟; 張大鵬; 楊騰方; 林慶雄; 黃明和; | 書刊名 | 麻醉學雜誌 |
卷 期 | 36:3 1998.09[民87.09] |
頁 次 | 頁133-136 |
分類號 | 416.54 |
關鍵詞 | 皮膚內注射; 疼痛衡量; Tramadol; Injection; Intradermal; Pain measurement; |
語 文 | 英文(English) |
中文摘要 | 背景:靜脈內存留tramadol與靜脈內存留lidocaine一樣,可有效地防止propofol 之注射痛。但此種週邊之件用,文獻從未提及。 方法:以雙盲之方式,我們在十位自願者之前臂皮膚內注射tramadol 25毫克,lidocaine 5 毫克,及生理鹽水0.5毫升,注射痛與其局部麻醉之程度(針刺,輕觸,冷溫)予以定時測 量。 結果:5% tramadol 和1% lidocaine一樣,在皮膚內注射時,前30分鐘比起生理鹽水有 降低針剌,輕觸,冷溫之作用(p<0.01)。 結論:在皮膚內注射5% tramadol 和1% lidocaine一樣,可產生局部麻醉之作用。 |
英文摘要 | Background:We observed that intravenous retention of tramadol with a pnecumatic tourniquet on the arm inflated to 70 mmHg for one minute could effectively reduce the subsequent propofol injection pain. Tramadol is a central-acting analgesic. The local analgesic effect of tramadol on reducing propofol injection pain is not well known. Method:To explore this problem we conducted a double-blind study on intradermal injections of tramadol 25mg, lidocaine 5 mg and normal saline(all in 0.5 ml volume) which were given to each of the 10 healthy volunteers on the forearm at random. Pain on injections and the degree of local analgesia to pinprick, light touch and cold at each injection site were scored on a 0-4 scale at designated intervals. Results:5% tramadol, similar to 1% lidocaine, rendered loss of sensatiion to pin prick, light touch and cold for 30 min after intradermal injection as compared with normal saline(p<0.01). Conclusions:We concluded that intradermal injection of tramado of lidocaine can produce local anesthetic effect. |
本系統中英文摘要資訊取自各篇刊載內容。