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題 名 | Oral Manifestations of Human Immunodeficiency Virus-Infected Patients in Taiwan=臺灣人類免疫缺乏病毒感染患者之口腔表徵 |
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作 者 | 江俊斌; 闕玲惠; 林思洸; 陳茂源; | 書刊名 | 臺灣醫學會雜誌 |
卷 期 | 97:9 1998.09[民87.09] |
頁 次 | 頁600-605 |
分類號 | 415.69 |
關鍵詞 | 人類免疫缺乏病毒感染患者; 口腔; Oral lesions; Oral hairy leukoplakia; Oral candidiasis; HIV infection; |
語 文 | 英文(English) |
英文摘要 | To understand the characteristic clinical features of human immunodeficiency virus (HIV)-related oral lesions and determine the prevalence of various oral lesions in HIV-infected patients in Taiwan, we conducted a cross-sectional study of 207 HIV-infected patients at the Taipei Municipal Institute for Venereal Disease Control. Overall, 108 (52.2%) patients had at least one oral lesion. The most common oral manifestation of HIV infection among these 207 patients was oral hairy leukoplakia (OHL, 29.5%), followed by candidiasis (12.1%), xerostomia (10.6%), aphthous ulcers (8.7%), and linear gingival erythema (5.8%). Less frequently encountered oral lesions included leukoplakia (1.9%), papilloma (1.4%), necrotizing ulcerative periodontitis (1.0%), Kaposi's sarcoma (1.0%), herpes simplex (0.5%), Burkitt's lymphoma (0.5%), and parotid gland enlargement (0.5%). Thirty-one (15%) patients had multiple oral lesions, Patients with oral candidiasis or multiple oral lesions had significantly lower mean CD4 lymphocyte counts and CD4/CD8 lymphocyte ratios than those without any oral lesions (p < 0.05). Chi-square analysis revealed that patients with CD4 lymphocyte counts below 200 cells/mm□ were more prone to have OHL (p< 0.002), oral candidiasis (p< 0.001) and multiple oral lesions (p < 0.001). Those with CD4/CD8 lymphocyte ratios below 0.4 were more likely to have OHL (p 0.02), oral candidiasis (p 0.01) and multiple oral lesions (P < 0.02) than those with higher counts. In conclusion, the occurrence of oral lesions, especially OHL and oral candidiasis, is fairly common in Taiwanese HIV-infected patients. |
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