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題名 | Antibody to Hepatitis C Virus in Multitransfused Patients with β-Thalassemia Major=重度乙型海洋性貧血患者多次輸血對C型肝炎病毒抗體之研究 |
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作者 | 彭慶添; 蔡長海; 蔡輔仁; | 書刊名 | 中臺灣醫學科學雜誌 |
卷期 | 3:2 1998.06[民87.06] |
頁次 | 頁67-71 |
分類號 | 414.82 |
關鍵詞 | 重度乙型海洋性貧血; C型肝炎病毒; β-thalassemia major; Hepatitis C virus; HCV; |
語文 | 英文(English) |
中文摘要 | 本研究是以在一中台灣醫院接受輸血治療之重度乙型海洋性貧血患者56名,檢測其C型肝炎病毒抗體之表徵,發現52%有患者帶有C型肝炎病毒抗體。在例行C型肝炎病素篩檢之前就已接受輸血治療的患者身上,有更高的比例帶C型肝炎病毒抗體。一項1991年研究指出,台灣的損血者比歐洲國家有更高的血清疾病流行率。而在C型肝炎病毒抗體陽性及陰性患者之間,其血漿氨基轉移酵素及血鐵質濃度差異並不顯著。17例肝穿刺報告中有4例病理組織為CPH,7例為CAH,而其餘6例為血色沈著病。 |
英文摘要 | This study examined the presence of anti-HCV antibodies in a group of 56β-thalassemia major patients who received blood transfusions in a hospital in central Taiwan. Overall, 52% were found to be anti-HCV positive. A higher incidence of anti-HCV antibodies was found in patients who, during transfusion therapy, started receiving blood prior to routine screening for anti-HCV. A study indicated a higher seroprevalence among blood donors in Taiwan than in European countries in 1991. Differences in serum transaminase and ferritin concentrations between anti-HVC positive and negative patients were not significant. Results from 17 biopsies showed 4 histological diagnoses were consistent with CPH, 7 with CAH and 6 biopsies with hemochromatosis only. |
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