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題 名 | Reaction of Carbon Disulfide and O-Phenylene Diamine by Tertiary Amine in the Presence of Potassium Hydroxide=在氫氧化鉀存在下以三級胺催化二硫化碳和鄰苯烯二胺之反應 |
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作 者 | 劉炳郎; 王茂齡; | 書刊名 | 中國工程學刊 |
卷 期 | 21:3 1998.05[民87.05] |
頁 次 | 頁317-325 |
分類號 | 460.02 |
關鍵詞 | 合成2-硫醇基苯駢咪唑三級胺; 氫氧化鉀; Synthesis of 2-mercaptobenzimidazole; MBI; Tertiary amines; Potassium hydroxide; |
語 文 | 英文(English) |
中文摘要 | 本研究主要以三級胺為觸媒,在氫氧化鉀存在下,進行二硫化碳和鄰苯烯 二胺在水溶液和機溶劑之二相反應。在氫氧化鉀存在下,添和少量之三級胺 就能大大地促進化學反應之進行。而合成2-硫醇基苯駢咪唑(2-Mercapto- benzimidazole)之反應發生於有機相反應。然而,2-硫醇基苯駢咪唑鹽卻產生 於二氯化碳和水之界面,然後再溶於水溶液中。使用此種方法合成產物最大之 優點在於藉著添加酸性化合物於水溶液中便可得到固體晶將之2-硫醇基苯駢咪 唑產物。由實驗數據得知,我們得以提供此反應之機構。反應乃由二硫化碳和 三級胺首先進行產生一個活性中間體(R�衹-CS��),活性中間體再與鄰苯烯二胺 進行反應合成2-硫醇基苯駢咪唑。除此,由於添加之氫氧化鉀與反應副產物 H�特進行反應得以使反應加速進行,而二硫化碳與鄰苯烯二胺之二相反應可以 由擬一階反應速率定律來描述。 |
英文摘要 | The reaction of carbon disulfide and o-phenylene diamine catalyzed by tertiary amine in the presence of KOH in an aqueous solution/ organic solvent two-phase medium was carried out. The reaction was greatly enhanced by adding a small amount of tertiary amine in the presence of KOH. The reaction of synthesizing 2-mercaptobenzimidazole (MBI) first took place in the organic phase. However, the potassium salt of MBI, which was produced from the reaction of MBI and KOH at the interface between CH�浚l�畝nd H�烙, dissolved in the aqueous phase. The greatest advantage of using this process is that MBI in crystal form can then be precipitated from the aqueous solution by adding an acidic compound. Based on the experimental data, a reaction mechanism was proposed. The reaction of synthesizing MBI was first initiated by reacting CS�畝nd R�衹 to produce an active intermediate (R�衹-CS��).This active intermediate further reacted with ophenylene diamine to produce the desired MBI product. In addition, potassium hydroxide also reacted with H�特, which is a hyproduct from the synthesis of MBI, to enhance the reaction. the reaction of CS�畝nd C�碎��(NH��)�疳n a two-phase medium is described by a pseudo-first-or- der rate law. |
本系統中英文摘要資訊取自各篇刊載內容。