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| 題 名 | Colonoscopic Screening for Patients with Curative Resection of Colorectal Cancer |
|---|---|
| 作 者 | Shieh,Ming-jium; Wang,Cheng-yi; Wong,Jau-min; | 書刊名 | 醫學工程 |
| 卷 期 | 10:1 1998.02[民87.02] |
| 頁 次 | 頁40-44 |
| 分類號 | 416.245 |
| 關鍵詞 | 大腸宜腸癌; 大腸鏡篩檢; Colorectal cancer patient; Operation; Follow-up; Colonoscopy; |
| 語 文 | 英文(English) |
| 英文摘要 | We conducted a prospective study to evaluate the diagnostic yield of primary colonoscopy in patients three or more years after curative resection for colorectal cancer (CRC). During a five- year period (1992-1996), 238 patients (138 men and 100 women) were enrolled and underwent complete colonoscopy. Of these, 230 patients had previous surgery and 8 patients had a polypectomy for malignant polyps. The mean age at presentation for colonoscopy was 62.0 years. The mean duration between the first operation and screening colonscopy was 84 months (range, 36 to 489). Colonoscopic surveillance disclosed 6 cancers and 63 adenomas, giving a 29% diagnostic yield. Three cancer patients were found to have distant metastasis and had palliative treatment only. Five cases of small flat adenoma (Muto type) were detected, of which two (40%) had malignant transformation. This finding suggests that adenomas found in patients with a history of CRC surgery may progress to cancer at a different rate from those in average-risk people who have not had a previous CRC. In conclusion, although primary colonscopic screening for CRC after resection can give a relatively high diagnostic yield for colonic neoplasms, the rate of curative resection for metachronous CRC was only 50% We recommend its use for follow-up of high-risk patients, but further studies are needed to establish the optimum time intervals. |
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