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相關文獻
- Pulmonary Arteriovenous Malformation:Analysis of 10 Cases
- Diffuse Type Pulmonary Arteriovenous Malformations: Report of One Case
- Diffuse Type Pulmonary Arteriovenous Malformations Demonstrated by Lung Perfusion Scans: Two Case Reports
- Coexistence of Pulmonary and Cerebral Arteriovenous Malformations in a Male Adult
- Paraesophageal Hernia and Pulmonary Arteriovenous Malformation: Report of One Case
- 肺動靜脈畸形
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- Pulmonary Arteriovenous Malformations Mimicking Solitary Pulmonary Nodule with No Symptoms: A Case Report
- Pulmonary Arteriovenous Malformation Presenting as Brain Abscess
- Brain Abscess as the First Clinical Manifestation of Isolated Pulmonary Arteriovenous Malformation without Hereditary Hemorrhagic Telangiectasia: A Case Report
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題名 | Pulmonary Arteriovenous Malformation:Analysis of 10 Cases=肺動靜脈畸形:一教學醫院十位病例之分析 |
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作 者 | 王鶴健; 楊泮池; 郭壽雄; 陸坤泰; | 書刊名 | 臺灣醫學會雜誌 |
卷期 | 97:2 1998.02[民87.02] |
頁次 | 頁97-100 |
分類號 | 415.384 |
關鍵詞 | 肺動靜脈畸形; Pulmonary arteriovenous malformation; Hereditary hemorrhagic telangiectasia; Brain abscess; Osler-Weber-Rendu disease; Dyspnea on exertion; |
語文 | 英文(English) |
英文摘要 | Pulmonary arteriovenous malformation (PAVM) is an uncommon but not rare disease. It is very often associated with hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu disease, OWRD). Both conditions may be readily diagnosed at the bedside when carefulattention is given to clues from history taking and physical examination. Sometimes the clinical features may be neglected, delaying the diagnosis. The natural history of this disease is still incompletely understood because of the paucity of cases. This retrospective study was undertaken to evaluate the clinical manifestations and treatment options in patients with documented PAVM at the National Taiwan University Hospital between 1985 and 1997. Ten patients (4 men, 6 women) of documented PAVM were evaluated. Mean age at diagnosis was 37.8 years (range 22-63). Presenting symptoms included dyspnea on exertion, characteristics of OWRD, and major neurologic events. Six episodes of brain abscess occurred in three patients. The predominant location of PAVMs was the lower lobe. Solitary PAVM was more frequent in our patients (5/6) with OWRD than in other reports. The therapeutic options were: surgical resection (3 patients), embolotherapy (4), and no treatment (4). One patient, who refused treatment at first, developed a brain abscess later. There was no documented recurrence or growth of new PAVMs in patients who underwent surgical resection. Embolotherapy failed in one patient; no recanalization was found in the remaining patients. In conclusion, the diagnosis of PAVM may be subtle, but careful attention to historic clues and physica findings may lead to early diagnosis. Appropriate treatment is mandatory and may prevent the severe complications of PAVM. The debate about the preferred treatment seems likely to continue until more is known about the natural history of this disease. |
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