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題 名 | Primary Papillary Adenocarcinoma of the Rete Testis: Report of a Case and Review of Literature=原發性睪丸網乳突狀腺癌: 一病例報告及文獻回顧 |
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作 者 | 張保欽; 陳安; 于大雄; 李偉華; | 書刊名 | 醫學研究 |
卷 期 | 18:4 1998.01[民87.01] |
頁 次 | 頁254-259 |
分類號 | 415.87 |
關鍵詞 | 腺癌; 睪丸網; 轉移癌; 免疫化學染色; 電鏡; Adenocarcinoma; Rete testis; Metastatic carcinoma; Immunohistochemistry; Electron microscopy; |
語 文 | 英文(English) |
中文摘要 | 原發性睾丸網乳突腺癌極為罕見,通常易誤診為轉移癌。文中報告一七十五歲男性因其睾丸數月以來逐漸漲大,但並不覺得疼痛。至本院手術摘除並經病理切片鏡檢、免疫化學染色、及電鏡研究後確認為一極為罕見的原發性睾丸網乳突腺癌。此案例雖經手術治療及追加局部放射線治療,仍然在術後二十五週出現陰莖根局部皮膚轉移,二十八週出現腹水。據國外文獻報告此病一般預後不良,通常在診斷後二至十月內即死亡。很不幸的,此病例雖合病化學治療,仍於術後四十二週因此病死亡。 |
英文摘要 | Primary papillary adenocarcinoma of the rete testis if extremely rare and may be misdiagnosed as a metastatic carcinoma of the testis. A 75-year-old man was admitted due to progressive, painless, enlargement of his testes for several months prior to his first hospitalization. Bilateral orchiectomy was performed and confirmed to be a case of primary testicular cancer. The tumor cells manifested a transition to the normal epithelial cells of the rete testis. They grew in a papillary pattern with del cate fibrovascular cores and occasional psammoma bodies. By immunohistochemistry, this tumor was positive for carcinoembryonic antigen and cytokeratin, but negative for thyroglobulin, alpha-fetal protein, or placental alkaline phosphatase. Electron microscopy showed short microvilli of cytoplasmic border and invagination of nuclei. Twenty- five weeks after ofchiectomy combined with local radiotherapy, tumor metastasis to the penile foot skin was noted. Malignant tumor cells in ascites were found at the 28th weeks of hospitalization after first surgical therapy. He was dead from the tumor at the 42th weeks after surgery. |
本系統中英文摘要資訊取自各篇刊載內容。