查詢結果分析
來源資料
相關文獻
- 內分泌異常性之陰莖勃起障礙診斷及治療
- Titration Study of MUSE (Medicated Urethral System for Erection) in Erectile Dysfunction
- 臺灣地區83位中老年男性射精問題的研究
- Clinical Study of Oral Trazodone in the Treatment of 25 Impotent Patients
- Dynamic Infusion Cavernosometry and Cavernosography (DICC) in the Evaluation of Vasculogenic Impotence
- Priapism-- A Rare Presentation in Chronic Myeloid Leukemia: Case Report and Review of the Literature
- Long-term Follow-up of Intracavernous Injection of Vasoactive Agents in the Treatment of Impotence
- 勃起的生理及陽萎的病態生理
- 中醫藥治療勃起功能障礙之思路
- 男性性無能及其護理
頁籤選單縮合
題 名 | Clinical Study of Oral Trazodone in the Treatment of 25 Impotent Patients=使用Trazodone治療陽萎病人的臨床試驗 |
---|---|
作 者 | 郭育成; 劉詩彬; 謝汝敦; | 書刊名 | 中華民國泌尿科醫學會雜誌 |
卷 期 | 9:1 1998.03[民87.03] |
頁 次 | 頁7-11 |
分類號 | 415.8616 |
關鍵詞 | 陽萎; 勃起; Trazodone; Impotence; Erection; |
語 文 | 英文(English) |
中文摘要 | Trazodone這個口服抗憂鬱藥,曾經被報告說能延長正常男人的勃起時間、以及使 陽萎的病人獲得改善。我們使用Trazodone一天三次,每次五十毫克來治療二十五位陽萎病 人。有四位病人在第一週內停止用藥,其中三位是因為有嚴重的嗜睡現象,一位是因為小便 困難。剩下的二十一位病人中,四位被診斷為心理因性陽萎,十七位為器官性陽萎。經過四 周的用藥,利用問卷來評估效果。 對於用藥整體的有效率是52.4%。在器官性陽萎的病人裡面,治療效果在不同的年齡群 中並沒有顯著的差異。然而對於那些陽萎時間小於等於十八個月內的病人群,治療的有效率 (75.0%),卻遠大於陽萎時間超過十八個月的病人群(22.2%,P值等於0.0296%)。在這些病 人中性慾方面則沒有明顯的改變。 Trazodone 的副作用包括了高頻率的嗜睡(84%)、虛弱(48%)、口乾(40%)以及視力模糊 (24%),並且有兩位病人出現腎臟功能變差的現象。 總結來說,Trazodone對於一部份陽萎病人的治療是有效的,特別是對於陽萎時間在十 八個月以內的病人,治療效果較好。因此陽萎愈早被診斷,治療成功的機率愈大。Trazodone 的副作用需要小心的監測。我們仍需要一個更大型的雙盲試驗(Double-blind test)來確認它的 效果,以及決定它的最適劑量。 |
英文摘要 | Trazodone is an oral antidepressant that has been reported to prolong erections of potent men and to improve erections of impotent patients. We administered 50mg trazodone three times a day to twenty-five impotent patients. Four patients discontinued the medication within the first week due to severe drowsiness in three patients and difficulty in urination in one. Of the remaining 21 patients, four were diagnosed with psychogenic impotence and 17 with organic impotence. After four weeks of medication, the results were evaluated by questionnaires. The overall response rate to the medication was 52.4% Among the patients with organic impotence, there was no significant difference in response to the medication between the different age groups. However, the overall response rate to the medication was much higher in the patients who were impotent for 18 months or less (75.0%) than in the patients who suffered from impotency more than 18 months (22.2%, p=0.0296). There was no obvious change in libido in these patients. Side effects included a high percentage of drowsiness (84%), weakness (48%), dry mouth (40%) and blurred vision (24%). Impaired renal function also occurred in two patients. In conclusion, trazodone is effective for some impotent patients. It was more effective in treating patients who suffered from impotency for 18 months or less. Thus, the earlier impotence is diagnosed the better chance there is for successful treatment. The side effects should be monitored carefully. A large double-blind series is needed to confirm the results and determine the optimal dose of trazodone. |
本系統中英文摘要資訊取自各篇刊載內容。