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題名 | Halothane Requirement--A Comparison between Laryngeal Mask Airway Insertion and Endotracheal Tube Intubation in Pediatric Patients=小兒病患放置喉罩管及氣管內管所需要Halothane濃度的比較 |
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作者 | 李繼源; 吳慶堂; 汪志雄; 孫建安; 葉春長; 何善臺; | 書刊名 | 麻醉學雜誌 |
卷期 | 36:1 1998.03[民87.03] |
頁次 | 頁37-41 |
分類號 | 417.66 |
關鍵詞 | 吸入性麻醉劑:halothane; 氣管內置放術:喉罩管氣管內管小兒; Anesthetics inhalational:halothane; Intubation intratracheal laryngeal mask airway endotracheal tube pediatrics; |
語文 | 英文(English) |
中文摘要 | 背景:本研究目的在比較在小兒病患放置喉罩管( LMA )及氣管內管( ETT )所需要 halothane 的有效濃度 (EC □ )。 方法:48 位兒科病患( 10 月 -6 歲)接受體表手術經隨機分成二組,LMA 及 ETT。 經由麻醉氣體揮發器給予一預先決定的濃度 20 分鐘後,進行喉罩管及氣管內管的放置;病 患的反應分為有或無動作發生。50% 病患有效濃度 (EC □ ) 用 un-and-down 方法(每次 上升或下降 0.5% )求得,並計算 95% 信賴區間。 結果:喉罩管( LMA )放置的 halothane EC □為 1.5 ± 0.4% ( 95% 信賴區間為 1.4-1.7% ),而氣管內管放置的 halothane EC □為 2.3 ± 0.5% (95% 信賴區間為 2.1-2.5%)。二者呈現顯著並差異 (p<0.01),喉罩管對呼吸道的刺激反應較輕微。 結論:喉罩管比氣管內管可在較低的 halothane 濃度放置,呼吸道副作用較少。 |
英文摘要 | Background: The present study was to determine the effective concentration of halothane for insertion of laryngeal mask airway (LMA) and for intubation of endotracheal tube (ETT) in pediatric patients Methods:Forty-eight ASA class 1 patients, aged from 10months to 6 years, scheduled for minor elective surgery were randomly assigned to two groups i.e., LMA and ETT. The concentration of halothane effective in fifty percent of patients (EC □ ) was determined by the up-and-down method (with 0.5% as a step size). After the predetermined concentration of halothane delivered from a calibrated vaporizer was established and maintained for 20 min, LMA insertion or ETT intubation was attempted without the patient be ing curarized. The response of patient to LMA or ETT was reported either as "movement"or "non-movement". The effective concentration and associated 95% confidence limits were determined in each group. Results: An effective concentration of halothane for LMA insertion was 1.5 ± 0.4% (95% confidence limits 1.4-1.7%), whereas that for ETT intubation was 2.3 ± 0.5% (95% confidence limits 2.1-2.5%). The difference between these two values was statistically significant (p<0.01). Airway reflexes after LMA insertion were minimal. Conclusions: The insertion of LMA could be performed at a significantly less halothane concentration in comprison with ETT intubation in children. |
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