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題 名 | Importance of Docosahexaenoic Acid as an Infant Nutrient=DHA對嬰兒營養成分之重要 |
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作 者 | 藤本健四郎; | 書刊名 | 食品科學 |
卷 期 | 24:6 1997.12[民86.12] |
頁 次 | 頁658-666 |
專 輯 | 「張駟祥教授紀念研討會--食品之保健功效」研討會論文專輯 |
分類號 | 411.374 |
關鍵詞 | 嬰兒; 營養成分; Docosahexaenoic acid; Arachidonic acid; Infant formula; Nutrition; |
語 文 | 英文(English) |
英文摘要 | The capability of microsomal synthesis of docosahexaenoie acid(DHA) in brain of Japanese monkeys was dependent on age, and in neonate brain, DHA was hardly synthesized. On the other hand, DHA synthetic activity in liver was independent of age but remained very low. The specific activity of glycerophospholipid synthesis in cortical gray matter, i. e., activation of long chain polyunsaturated fatty acids, acylation of lysophosphoglyceride, and phosphorylation of diacylglyeerol, was maximal at the neonatal stage and gradually decreased with age. The effect of dietary supplementation of DHA on pregnant rats showed that the DHA levels in the cerebral cortex were higher in the DHA group than in the control (soya) group. The difference was greatest during the lactation period, and DHA intake was more effective in elevating the concentration of DHA in sucklingpups than in weaning pups. Human breast milk contains DHA and arachidonic acid, whose levels are highest in colostmm. These results suggest that breast milk provides DHA and arachidonic acid to neonates who require a large quantity of these highly unsaturated fatty acids for brain development. The DHA and arachidonic acid levels in the erythrocytes of low birth weight human infants who had been given different ratios of breast milk/infant formulas containing 0.3% DHA and 0.1% or 0.05% arachidonic acid showed fairy good positive correlation with the ratio of breast milk/infant formula. It is suggested that the supplementation of more DHA and arachidonic acid in infant formula is necessary. |
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