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頁籤選單縮合
題名 | Bacterial Isolates and Antimicrobial Susceptibility from 400 Burn Patients=灼傷菌株和制菌劑的敏感度:從400個灼傷病人的分析 |
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作者 | 陳添興; 楊瑞永; | 書刊名 | 中華民國急救加護醫學會雜誌 |
卷期 | 8:3 1997.09[民86.09] |
頁次 | 頁93-102 |
分類號 | 416.141 |
關鍵詞 | 菌株; 制菌劑敏感度; 傷口感染; Bacterial isolate; Antimicrobial susceptibility; Wound infection; |
語文 | 英文(English) |
中文摘要 | 灼傷傷口感染仍是灼傷病人死亡的最主要原因。瞭解灼傷細菌的菌株和其制菌劑的敏感性是控制灼傷傷口感染的第一步。我們從400個灼傷病人,共2470個細菌培養報告來進行這次研究。Pseudomonas aeruginosa(10.6%)為最主要的菌株,敏感于imipenem-cilastatin(90%)和cefatazidime(51%);次要的菌株為Enterococcus(9.6%), 敏感于ampicillin(91%)和vancomycin(73%);第三次要的菌株為starhylococcus epidermidis(5.9%),敏感于vancomycin(91%)和cefamandole(79.5%);第四次要菌株為staphylococcus aureus(5.4%),敏感于vancomycin(99%)和cefamandole(65%)。另外,局部制菌劑Silver sulfadiazine的常見副作用為白血球減少(佔7.5%), Mafenide acetate的副作用則為疼痛(佔85%)。灼傷病人發生的病變為敗血症(13.5%),嚴重傷口感染(5%),和肺炎(5%)。灼傷病人的死亡率為5.3%。 |
英文摘要 | Burn wound infection continues to be the most common cause of burn mortality. Identifying of the bacterial isolates and their antimicrobial susceptibility is an important step in controlling burn infection. Four hundred burn patients with 2470 culture specimens were retrospectively by reviewed. Pseudomonas aeruginosa (10.6%) was the most common isolate, susceptible to imipeneim-cilastatin (90%) and cefatazidime (81%);followed by Enterococcus species (9.6%), susceptible to ampicillin (91%) and vancomycin (73%); Staphylococcus epidermidis (5.9%), susceptible to vancomycin (91%) and cefamandole (79.5%); and Staphylococcus aureus (5.4%), susceptible to vancomycin (99%) and cefamandole (65%). The main side effects of topical agents were leukopenia (7.5%) with silver sulfadiazine and pain (85%) with mafenide acetate. Morbidity among the burn patients included sepsis (13.5%), severe wound infection (5%), and pneumonia (5%). The mortality rate in this series was 5.3%. |
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