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題名 | 類固醇治療中發生急性肝衰竭之經驗--病例報告=The Experience of Acute Hepatic Failure during Steroid Treatment--A Case Report |
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作者姓名(中文) | 黃文玲; 葉思伯; 林瑞宜; 呂恒明; | 書刊名 | 中華皮膚科醫學雜誌 |
卷期 | 15:3 1997.09[民86.09] |
頁次 | 頁231-235 |
分類號 | 415.53 |
關鍵詞 | 類固醇治療; 急性肝衰竭; Steroid; Viral hepatitis; Acute hepatic failure; |
語文 | 中文(Chinese) |
中文摘要 | A 81-year-old asymptomatic hepatitis B carrier presented with lower limb itching skin rashes for 2 months.bullous pemphigoid was diagnosed by histopathology and immunofluorescent method.the skin lesion improved during steroid treatment.However, fatal acute hepatic failure developed during tarper- ing steroid. We experienced that immunosuppressive treatment in patient with viral hepatitis could be risky.It may be related to increase viral replication followed by immunosuppressive treatment which lead to acute massive hepatic necrosis. therefor, it is essential to use steroid cautiously and monitor viral activity and liver biochemical test during immunosuppressive treatment. |
英文摘要 | 一位81歲無症狀B型肝炎帶原者,主訴下肢皮疹搔癢2個月,經組織病理及免疫螢 光色法診斷為類天�紗H,以類固醇治療後,病灶明顯改善,惟於減藥期間,發生急性肝衰 竭死亡。我們經驗到對病毒性肝炎的患者,免疫抑制劑之治療具危險性,可能因為治療期間 病毒再活化,造成急性肝壞死。所以,在治療期間,必須小心使用類固醇和監測病毒複製 活性及肝能。(中華皮誌 15;231-235,1997) |
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