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題名 | 原發性皮膚Rosai-Dorfman病--病例報告=Primary Cutaneous Rosai-Dorfman Disease--Report of a Case |
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作者 | 楊進隆; 黃玄贏; 何宜承; 陳維仁; Yang, Chin-lung; Huang, Hsuan-ying; Ho, Ji-chen; Chen, Wei-jen; |
期刊 | 中華皮膚科醫學雜誌 |
出版日期 | 19970900 |
卷期 | 15:3 1997.09[民86.09] |
頁次 | 頁194-199 |
分類號 | 415.7 |
語文 | chi |
關鍵詞 | 原發性皮膚Rosai-dorfman病; Rosai-dorfman disease; Sinus histiocytosis with massive lymphadenopathy; Emperipolesis; S-100 protein antibody; Primary cutaneous rosai-dorfman disease; |
中文摘要 | Rosai-dorfman disease (RDD) (Sinus histiocytosis with massive lympha- denoathy)is a systemic proliferation of cells that resemble the sinus histiocy- tes of lymph nodes.Cutaneous lesions are usually associated with nodal or other extranodal location.We herein describe a female with RDD clinically limited to the skin.The patient presented with asymptomatic dermal nodules on the abdominal wall.Histologically, the lesion consisted of a proliferation of large histiocy- tes occasionaly showing emperipolesis.Staining with S-100 protein antibody showed marked cytoplasmic positivity in the histiocytes.No other foci could be detected by thorough physical examination.Primary cutaneous Rosai-Dorfman disease is rarely reported in the literature. |
英文摘要 | Rosai-dorfman disease(RDD)(又叫竇組織球細胞增生症合併大量淋巴結病變: sinus histiocytosis with massive lymphadenopathy, SHML)是一種類似淋巴結之淋巴竇 中組織球細胞的系統性增生。皮膚的RDD通常有淋巴結或結外的病灶。我們報告一侷限於皮 膚的RDD病例。病人在腹脅近肚臍處有一皮內的硬塊,組織切片下可見吞噬各類細胞的大型 組織球細胞之增生,用S-100蛋白抗體染色,則可見明顯細胞質肉染色。全身檢查並無其它 病灶之發現。純粹皮膚的RDD在文獻上,很少有人報告。 |
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