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題 名 | 多發性膽固醇栓子症候群=Multiple Cholesterol Embolization Syndrome |
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作 者 | 陳高揚; 曾春典; | 書刊名 | 內科學誌 |
卷 期 | 8:4 1997.12[民86.12] |
頁 次 | 頁151-155 |
分類號 | 415.384 |
關鍵詞 | 粥腫栓子; 多發性膽固醇栓子症候群; Atheroemboli; Multiple cholesterol embolization syndrome; |
語 文 | 中文(Chinese) |
中文摘要 | 多發性膽固醇栓子症候群是指動脈粥腫塊處的膽固醇結晶散落到週邊的小動脈, 病理學上的診斷是靠生檢或病理解剖的標本上,在小動脈的內腔內找到光學上光亮的膽固醇 製片或雙折射性的膽固醇結晶。在病理解剖的報告中,受影響的組織幾乎包括所有的器官, 此症候群多在死後才診斷,臨床上的生前診斷較少,這是因為它所影響的是小的動脈,發生 時其症狀與徵象很輕微,因此臨床上除非非常細心,否則很難診斷出來。生前的診斷通常是 由肌肉、皮膚和腎臟的生檢而確定。最適當的治療法尚待建立,預後與全身侵犯的程度有關, 死因多半是多因子性的。由於膽固醇栓子症候群多發生於有動脈粥腫化的老年病人進行侵襲 性的主動脈操作之後,因此注意篩選高危險群病人並小心操作最為重要。 。 |
英文摘要 | Multiple cholesterol embolization syndrome results from the embolization of cholesterol crystals from atherosclerotic blaques lining the walls of major arteries. Pathologically, optically clear cholesterol clefts or birefringent cholesterol crystals can be found within the lumina of small arteries or arterioles of biopsy or autopsy specimens.In autopsy secies, the involved tissues include almost all organs. Multiple cholesterol embolization syndrome was often diagnosed post-mortem rather than by premortem biopsy, since its involvement in a small artery may cause only mild symptoms and signs, and thus easily remain unrecognized. Premortem diagnosis were established most commonly by biopsy of the muscle, skin and kidney. Treatment remains to be established. The prognosis is related to the extent of systemic involvement. The cause of death was most often multifactorial. Since it was most often developed after an invasive manipulation of the aorta in elderly patients with aortic atheroclerosis, careful screening of the high risk patients and delicate manipulation are the most important in prevention. |
本系統中英文摘要資訊取自各篇刊載內容。