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相關文獻
- Acute Myelomonocytic Leukemia Preceded by Secondary Amenorrhea and Presenting with Central Diabetes Insipidus: A Case Report
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題 名 | Acute Myelomonocytic Leukemia Preceded by Secondary Amenorrhea and Presenting with Central Diabetes Insipidus: A Case Report=急性骨髓性單核球白血病發病前有繼發性無月經症發病時以中樞型尿崩症表現:一病例報告 |
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作 者 | 顏厥全; 曾成槐; 劉俊煌; 邱宗傑; 謝瑞坤; 王緯書; 陳博明; | 書刊名 | 中華醫學雜誌 |
卷 期 | 60:4 1997.10[民86.10] |
頁 次 | 頁213-218 |
分類號 | 415.635 |
關鍵詞 | 急性骨髓性白血症; 無月經症; 尿崩症; 全腦下垂體低下症; Acute myeloid leukemia; Amenorrhea; Diabetes insipitus; Panhypopituitarism; |
語 文 | 英文(English) |
中文摘要 | 一位二十八歲女性在本院第一次住院前兩個月發生繼發性無月經症,然後被發現罹患全腦下垂體低下症以及急性骨髓性單核球白血病。病人在經過引導化學治療後得到完全緩解。其後她又接受四次交化學治療,包括一次高劑量Ara-C的治療以及十四天的G-CSF注射以收集周邊血造血母細胞。之後她接受了周邊血造血母細胞移植。但不幸白血病於移植後四個月復發。病人于復發很快因嚴重的電解質不平衡及敗血症而死亡。病人的腦下垂體功能在治療後僅部份恢復。在整個臨床過程中,並未發現有實驗室或影像學的證據來顯示中樞神經系統被白血病侵犯。 |
英文摘要 | The patient, a 28 year-old female, recieived treatment for secondary amenorrhea two months before her first admission to our hospital. She was later found to have central type diabetes insipidus and acute myelomoncytic leukemia. A diagnosis of panhypopituitarism was established but there was no laboratory or radiological evidence of neuroleukemia. Complete remission was obtained after one course of induction chemotherapy. She received four more courses of chemotherapy including one course of high-dose cytosine arabinoside (Ara-C) and 14-day granulocytic colony-stimulating factor (G-CSF) for peripheral blood stem cell (PBSC) mobilization. Then she received autologous PBSC transplantation (Auto-PBSCT). Unfortunately leukemia relapsed 4 months after transplantation. The patient expired soon due to severe electrolyte imbalance and sepsis. Throughout the whole course, her pituitary function was only partially recovered after treatment and there was no laboratory or radiological evidence of CNS leukemia. |
本系統中英文摘要資訊取自各篇刊載內容。