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題名 | Hormonal Changes Associated with Menstrual Cycle Have no Definite Influence on Ocular Pressure=月經周期激素變化對眼內壓無明確影響 |
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作者 | 艾穆拉; 黃陽濱; 席曉蓉; 吳向東; | 書刊名 | Proceedings of the National Science Council : Part B, Life Science |
卷期 | 21:2 1997.04[民86.04] |
頁次 | 頁49-53 |
分類號 | 417.12 |
關鍵詞 | 月經周期; 激素變化; 眼內壓; Menstrual cycle; Ocular tension; Sex hormone; Tonometry; |
語文 | 英文(English) |
中文摘要 | 背景:目前認為孕激素和雌激素(單獨或聯合)用葯可以影響到眼內壓(IOP), 雖然有一些文獻持否定態度。 隨月經周期而變化的激素與 IOP 之間的關係目前尚不明瞭。 除去了可干擾 IOP 的影響因素後, 本實驗試圖瞭解生理性隨月經周期而變化的激素是否引 起 IOP 的改變。 方法:20 個已婚同一年齡組且不用避孕葯的婦女在一個月經周期中, 每日用 Goldmann 壓 平眼壓計檢測 IOP, 並測定激素血液度, 包括:黃體生成素( LH )、卵泡刺激素( FSH )、雌酮( E1 )、雌二醇( E2 )、孕激素和睪酮。 結果:20 個對象的 IOP 值隨月經周期不同的時間而變化,然而未發現不同時期各激素水平 與 IOP 間的確切關係。 結論:隨月經周期發生的激素改變對 IOP 無明確的影響。 |
英文摘要 | Background: Despite some findings to the contrary, it would appear that pharmacological doses of progesterone and estrogen (alone or in combination) can influence intraocular presure (IOP). The relationship between hormonal changes associated with the menstrual cycle and intraocular pressure is not clearly understood. After elimination of those factors that can affect IOP, the present study investigated whether physiological hormonal changes associated with the menstrual cycle have a correlation with intraocular pressure. Methods: Intraocular pressure and the concentrations of circulating hormones, namely, the luteinizing hormone (LH), follicle-stimulating hormone (FSH), estrone (E1), estradiol (E2), progesterone, and testosterone, of twenty married women of the same age groups were recorded daily throughout a menstrual cycle. None was taking any contraceptives in any form. The intraocular pressure was measured using a Goldmann applanation tonometer. Results: The intraocular pressure values fluctuated in each of the twenty subjects at various times of the cycle; however, they were not definitely correlated with the different phases of the cycle. This study failed to find any correlation between IOP and progesterone or estradiol levels. |
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