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| 題 名 | Effects of Salmon Calcitonin and Bovine Parathormone on the levels of Serum Calcium and Inorganic Phosphorous, and the Histology of the Parathyroid Gland in the Snake, Acrochordus Granulatus (Schneider)=鮭魚抑鈣素及牛副甲狀腺素對蛇(Acrochordus Granulatus)血清鈣及無機磷濃度及副甲狀腺組織學之影響 |
|---|---|
| 作 者 | Warbhuwan,Anita P.; Padgaonkar,Arun S.; | 書刊名 | 動物研究學刊 |
| 卷 期 | 36:1 1997.01[民86.01] |
| 頁 次 | 頁64-69 |
| 分類號 | 415.147 |
| 關鍵詞 | 抑鈣素; 副甲狀腺素; 蛇; Calcitonin; Parathormone; Snake; |
| 語 文 | 英文(English) |
| 中文摘要 | 注射抑鈣素(10 IU/100g體重)至蛇Acrochordus granulatus,導致其血清鈣及無機磷當天稍為昇高。但在此後十四天試驗期間內與對照組相似,並無昇高。而鮭魚抑鈣素促使該蛇之副甲狀腺實質細胞肥大,細胞核亦增大。鮭魚抑鈣素處理後,未發現血鈣降低,應歸結於該動物副甲狀腺分泌足夠的副甲狀腺素因而對抗鮭魚抑鈣素之作用。 注射牛副甲狀腺素至Acrochordus granulatus引發高血鈣反應;注射後第一天開始昇高,第二天達高峰,第四天才降低。血清無機磷在注射後第二天的濃度,則稍降低。副甲狀腺主細胞在注射牛副甲狀腺素後,其細胞質廣泛出現空泡;而細胞核變小。本研究所得結論是副甲腺素在Acrochordus granulatus扮演調節鈣磷代謝,而抑鈣素可對抗副由狀腺素之作用。 |
| 英文摘要 | Administration of salmon calcitonin in the snake, Acrochordus granulatus, at a dose of 10 IU/100 g body weight, resulted in a slight rise in the levels of serum calcium and inorganic phosphorous on day 1 as compared to the controls. There-after, these levels remained within normal limits throughout the course of the experiment. Snakes treated with calcitonin showed hypertrophy of the parenchymal cells of the parathyroid gland. The nuclei of these cells increased in size. The lack of hypocalcemic response in A. granulatus after calcitonin administration has been attributed to an adequate secretion of parathormone from the parenchymal cells of the parathyroid gland which counteracts the action of calcitonin. The hypertrophy of the parenchymal cells in the treated snakes support such a view. Administration of parathormone in A. granulatus evoked a hypercalcemic response on day 1, which reached a peak on the 2nd day and thereafter, showed a decline (4th day). The serum inorganic phosphorous level in the parathormone-treated snake showed a slight decrease on the 2nd day of treatment. The chief cells of the parathyroid glands of the parathormone-treated snakes showed extensive vacuolation in the cytoplasm. The nuclei of the cells decreased in size. The above experiments lead us to conclude that parathormone plays a pivotal role in the control of calcium and phosphate metabolism in the snake under study, and that calcitonin counteracts the action of parathormone. |
本系統中英文摘要資訊取自各篇刊載內容。