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題 名 | Ketoacidosis with Hyperglycemia in Heavy Drinkers: A Report of 12 Cases=大量飲酒者併有酮酸中毒及高血糖:十二例報告 |
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作 者 | 盧文聰; 陳光文; 林仁德; 黃鴻碩; 李青蓉; 黃瑞珊; | 書刊名 | 長庚醫學 |
卷 期 | 20:1 1997.03[民86.03] |
頁 次 | 頁34-38 |
分類號 | 418.82 |
關鍵詞 | 酮酸中毒; 高血糖; 酗酒; Ketoacidosis; Hyperglycemia; Heavy drinkers; |
語 文 | 英文(English) |
中文摘要 | 背景:大量飲酒(每日超過45克酒精)可能是糖尿病的成因之一。短期而言,酗酒易發生的臨床表現酮酸中毒,糖耐受不良及胰臟發炎。酗酒發生的酒精性酮酸中毒Alcoholic Ketoacidosis併高血糖很像糖尿病酮酸中毒Diabetic Ketoacidosis。本研究目的在描述無糖尿病病史之酗酒者以酮酸中毒與高血糖表現之案例的臨床特徵。 方法:本研究主要是從1989年7月到1992年7月間,1253位糖尿病住院病人資料中找到十二位酗酒同時表現出酮酸中毒及高血糖,但未曾有糖尿病病史的病人,他們都符合糖尿病酮酸中毒的標準。 結果:糖化血色素值高於正常值者被診斷為併有糖尿病,分析這些病人之糖化血色素值發現:十位病人數值上升;另外兩位正常者一位六個月後數值升高,一位經門診追蹤數年後,發現在無治療情況下,其值正常且血糖值也正常。 結論:酗酒併酮酸中毒及高血糖時,大多數有糖尿病且其糖化血色素值高於正常值。在我們的研究中,唯一的糖化血色素正常的女性患者在最初被診斷為DKA事後追蹤認為她應該是一個AKA而不是一個DKA的病人 |
英文摘要 | BACKGROUND: Heavy alcohol intake (> 45g daily) might be a cause of diabetes. The short-term risks of heavy alcohol intake include ketoacidosis, glucose intolerance and pancreastitis. Alcoholic ketoacidosis (AKA) in combination with hyperglycemia mimics diabetic ketoacidosis (DKA). We described the characteristics of heavy drinkers with ketoacidosis and hyperglycemia but without a prior history of diabetes. METHODS: Tweleve habitually heavy drinkers who had not been previously diagnosed as diabetes were indetified by reviewing the records of diabetic patients admitted to Chang Gung Memorial Hospital from 1989 to 1992. All of the them met DKA criteria. RESULTS: Elevated glycohemoglobulin (HbAlc) level is an indicator for the diagnosis of diabetes. Among these 12 patients, 10 had elevated levels of HbAlc and 2 had normal HbAlc levels. Of these 2 patients, 1 had an elevated level of HbAlc 6 months later; the other who was a female who after observation, had normal levels of HbAlc and glucose for the follow-up of two years. CONCLUSIONS: We found that most heavy drinkers with both ketoacidosis and hyperglycemia also had diabetes as indicated by high levels of HbAlc. The only female patient had normal HbAlc and was diagnosed as AKA rather than DKA. |
本系統中英文摘要資訊取自各篇刊載內容。