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頁籤選單縮合
題 名 | Premedication with Diclofenac and Prednisolone to Prevent Postoperative Pain and Swelling after Third Molar Removal=拔除智齒前給予Diclofenac和Prednisolone對於術後疼痛及腫脹的影響 |
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作 者 | 林子欽; 雷文天; 張哲壽; | 書刊名 | 中華醫學雜誌 |
卷 期 | 58:1 1996.07[民85.07] |
頁 次 | 頁40-44 |
分類號 | 416.953 |
關鍵詞 | 非類固醇抗發炎藥物; 類固醇; 智齒拔除; NSAID; Steroid; Third molar removal; |
語 文 | 英文(English) |
中文摘要 | 背景 術前給予非類固醇抗發炎藥物或類固醇已經證實能夠減少拔除 智齒後的後遺症,然而較少文獻提到兩者合用的效果。本文目的是要評估拔除 智齒前給予這兩類藥物是否能夠更有效減少術後的疼痛及腫脹。 方法 A組病人在拔除某一側上下智齒前給予50毫克diclofenac,拔除另一側時 給予安慰劑;B組病人則給予50毫克diclofenac加上10毫克prednisolone或是安 慰劑。術後記錄疼痛、腫脹及張口程度。 結果 術前給予50毫克diclofenac較安慰劑有顯著的止痛消腫作用,若再加以 prednisolone則消腫效果增加。 結論 拔除智齒前合併使用diclofenac和prednisolone可得到良好的術後止痛和 抗發炎效果。 |
英文摘要 | Background. Nonsteroidal anti-inflammatory drugs (NSAIDs) and steroid are able to effectively reduce the postoperative sequelae after impacted third molar removal. However, few studies have evaluated the activity of the combinant effects of these two drugs. The purpose of this study was to evaluate whether a single dose of prednisolone, taken orally before operation, would increase the effects of diclofenac in preventing pain and swelling after surgical removal of impacted third molars. Methods. Thirty healthy patients requiring surgical removal of four third molars were randomly assigned to two groups. In group A, patients were preoperatively given 50 mg of either diclofenac or placebo when impacted teeth were removed on each side. In group B, in addition to 50 mg of diclofenac, 10 mg of prednisolone or placebo was administered. Postoperative pain, swelling and range of mouth opening were recorded. Results. Preoperative administration of 50 mg of diclofenac could relieve pain and swelling more than the placebo. Additional 10 mg of prednisolone could further reduce swelling. Conclusions. The combination of diclofenac and prednisolone has a better analgesic and anti-inflammatory effect. |
本系統中英文摘要資訊取自各篇刊載內容。