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題 名 | Relationship Between C14 Urea Breath Test Values and Solid-Phase Gastric Empyting Time in Non-Ulcer Dyspepsia Patients=非潰瘍性消化不良病患之碳14尿素呼氣數值與固態胃排空時間之關係 |
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作 者 | 王以仁; 陳儉鏗; 吳國良; 賴啟賢; 張繼森; 潘錫光; 黃志焜; 高嘉鴻; | 書刊名 | 中華醫學雜誌 |
卷 期 | 57:4 1996.04[民85.04] |
頁 次 | 頁260-265 |
分類號 | 415.509 |
關鍵詞 | 碳14尿素呼氣法; 胃排空時間; 幽門螺旋桿菌; 非潰瘍性消化不良症; Carbon-14 urea breath test; Gastric emptying time; Helicobacter pylori; Hp; Non-ulcer dyspepsia; |
語 文 | 英文(English) |
中文摘要 | 背景:非潰瘍性消化不良(non-ulcer dyspepsia;NUD)在臨床上常常是以胃炎的型態表現,其中許多病人在胃黏膜上發現有幽門螺旋桿菌存在,而胃蠕動異常及胃排空延緩在臨床上也常見到,因此幽門螺旋桿菌對於胃蠕動異常之影響頗值得探究。 方法:本研究係由門診任意選取78位非潰瘍性消化不良病患及30位正常人,採用十分鐘之碳14尿素呼氣法來定量幽門螺旋桿菌及Tc-99m phytate固態食物胃排空檢查來進行兩者間之相關研究。同時探討性別、年齡及幽門螺旋桿菌感染之有無,對病人固態胃排空時間之影響。 結果:幽門螺旋桿菌率在患者中達59%且隨著年齡之增長而明顯增加(p=0.0091)。但是固態胃排空時間或碳14尿素呼氣數值在不同年齡層之病人間並無統計學上的差別。不論幽門螺旋桿菌感染與否,患者之固態胃排空時間相差不多且均較正常人有顯著延緩現象,且固態胃排空時間和碳14尿素呼氣數值之高低無關。 結論:利用核子醫學胃排空時間檢查可以發現非潰瘍性消化不良病患有明顯之胃蠕動延緩現象,但是幽門螺旋桿菌之感染與否,對於胃蠕動異常之嚴重程度並無明顯相關。 |
英文摘要 | Background: Non-ulcer dyspepsia (NUD) is a poorly understood syndrome often found with endoscopic evidence of gastritis; Helicobacter pylori (Hp) is a common and important cause of gastritis. In the recent literature, gastric hypomotility is thought to be a cause of NUD. Thus, this investigation studied the relationship between Hp and delayed gastric empting in NUD patients. Methods: Using a radionuclide-labelled solid meal to calculate gastric emptying time (GET) of 78 NUD patients. The carbon-14 urea breath test (C14 UBT) was used to quantitate Hp infection. Results: The prevalence of Hp infection in patients with NUD reached 59%. There was a strong association of Hp infection with advanced age (p=0.0091). There was no significant difference between solid-phase GET and C14 UBT values among three different age groups (young, middle, old) of NUD patients. There was no difference among sex, age, body weight and solid-phase GET between Hp-positive and Hp-negative NUD patients. However the solid-phase GET was significantly prolonged in patients with NUD, compared with the controls. Conclusions: Solid-phase GET is not correlated with the C14 UBT values, and Hp gastric colonization does not account for dyspeptic syndrome in NUD patients. |
本系統中英文摘要資訊取自各篇刊載內容。