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題名 | Surgical Management of Pituitary Adenomas=腦垂腺瘤的外科療法 |
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作者 | 洪純隆; 王致仁; | 書刊名 | 中華民國外科醫學會雜誌 |
卷期 | 28:5 民84.09-10 |
頁次 | 頁353-360 |
分類號 | 416.291 |
關鍵詞 | 腦垂腺瘤; 外科療法; Surgical results; Functional classification; Pituitary adenoma; |
語文 | 英文(English) |
中文摘要 | 本研究提出過去七年間,高雄醫學院神經外科使用免疫組織化學染色法來作腦垂腺瘤功能性分類、外科手術的結果及術後長期追踪的分析。 本系列報告中,自1986年至1993年七年中共有130個腦垂腺瘤的病例經確定診斷並接受手術治療,其中男性62例,女性的例,他們的年齡自15歲至78歲,平均年齡為43.4歲。大多數病人接受經蝶竇腦垂腺瘤摘除術,只有6例使用經額葉開顱術移除腦垂腺瘤。電腦斷層攝影及磁振掃描顯示有102例是巨大型腺瘤,28例是微小型腺瘤。 根據我們提出的分類法,最常見的分泌性腺瘤是促乳素腺瘤,有58例,占44.6%;次為生長素腺瘤,有15例,占11.5%。非功能性腺瘤則有26例,占20%,多由於腫瘤的質塊效應造成的神經受損或腦垂腺功能低下而被診斷出來。另有12例是分泌一種以上腦垂激素的混合型腺瘤。 本系列中沒有手術死亡的病例,罹病例有7例占5.4%,手術效果及追踪結果令人感到鼓舞。 |
英文摘要 | A functional classification using immunohistochemical staining was proposed for treating pituitary adenomas at this Hospital during the past seven years. Criteria for tumor grading, the surgical approaches used, the outcomes of treatment and long-term follow-up are presented. In this series, there were 130 patients with pituitary adenomas who were operated on between 1986 and 1993, including 62 male and 68 female patients. Patient ages ranged from 15 to 78, with an average of 43.4 years. Most patients underwent transsphenoidal approaches to remove pituitary tumors, and only six cases used transfrontal approaches. On brain CT scans and MRIs, 102 cases found to have macro-adenomas, and 28 with microadenomas. According to the proposed classification, the most common hypersecreting pituitary tumors were prolactinomas (58 cases, 44.6%), while GH-secreting tumors were the second most common (15 cases, 11.5%). Nonfunctioning pituitary tumors (26 cases, 20.0%) were usually found to have signs and symptoms of mass effect and hypopituitarism. There were also 12 cases of mixed type tumors secreting more than one kind of pituitary hormone. There were no mortalities, and the morbidity rate was 5.4% (7 in 130 cases). The overall surgical outcomes are encouraging. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。