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題名 | Medullary Thyroid Carcinoma=甲狀腺髓質癌 |
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作者姓名(中文) | 張原肇; 陳廣天; 張耀仁; 廖廣義; | 書刊名 | 中華民國外科醫學會雜誌 |
卷期 | 28:4 民84.07-08 |
頁次 | 頁285-290 |
分類號 | 415.931 |
關鍵詞 | 甲狀腺髓質癌; Medullary thyroid carcinoma; Pheochromocytoma; Multiple endocrine neoplasia; Calcitonin; Thyroidectomy; Modified radical neck dissection; |
語文 | 英文(English) |
中文摘要 | 甲狀腺髓質癌在甲狀腺的分類上是相當少見的。在臨床表現上可分為散發型與家族型,而家族型則又和多發性內分泌腫瘤有關。我們統計了自民國66年至民國82年(共17年)曾經在台大醫院接受過治療的髓質癌病人,共有30人,年齡分佈自15至78歲,其中有12個男性,18位女性,淋巴腺轉移發生在46.4%(13/30)的病人,有5位病人有遠處轉移的現象(3位在肺, 1位在肝, 1位在骨骼),另有4位病人證實或被懷疑是屬於多發性內分泌腫瘤第二型(MEN IIa)的病人,病人都伴有副腎上腺嗜鉻細胞癌,這兩種腫瘤均以外科手術為最佳治療。在本研究裡甲狀腺髓質癌3年存活率為93.7%,5年存活率為86.6%。 |
英文摘要 | Thyroid medullary carcinoma (MTC) is rare in the classification of thyroid cancer, with some association of multiple endocrine neoplasm (MEN) IIa. From January 1977 to December 1993, 30 patients with thyroid medullary carcinoma were treated in this Hospital and then analyzed retrospectively. Data were obtained from medical records. There were 12 men and 18 women, ranging in age from 15 to 78 years, with a mean age of 45.13 years. Lymph node metastasis was observed in 13 patients (46.4%), while distant metastsis was noted in 4 cases (lung metastasis in 3, liver metastasis in 1, case). Familial type were found in six patients (20%), three of whom are in the same family. Four cases of familial type were suspected to have MEN IIa syndrome (13.3%). Pheochromocytoma screening is especially important in these cases for the possibility of MEN IIa. Surgery is still the curative treatment for all MTC. However, pheochromocytoma has surgical priority. Twenty-five patients received thyroidectomy with curative intent. Two patients died 29 and 43 months, respectively, after operation. The five-year survival rate was 86.6% (13/15). |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。