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頁籤選單縮合
題名 | Penoscrotal Paget's Disease-A 10 Years Review=陰囊及陰莖部位柏哲氏疾病之十年回顧 |
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作者姓名(中文) | 吳傳昶; 葉發來; 方榮煌; | 書刊名 | 中華民國重建整形外科醫學會雜誌 |
卷期 | 4:3 1995.09[民84.09] |
頁次 | 頁144-149 |
分類號 | 416.275 |
關鍵詞 | 陰囊; 陰莖; 柏哲氏疾病; Extramammary Paget's disease; |
語文 | 英文(English) |
中文摘要 | 自1984年至1994年,台北榮民總醫院整形外科共治療17例陰囊及陰莖部位柏哲氏疾病的患者。病患的臨床表現,我們的治療方法,及患者的預後都予以分析討論。 對於手術切除病理標本中6例柏哲氏細胞局限於上皮層且手術標本邊緣無柏哲氏細胞者,均無局部復發或遠處轉移。但是如果柏哲氏細胞侵犯至真皮層,即使手術切除標本邊緣無殘留柏哲氏細胞,在9例中仍有4例發生局部復發,3例遠處轉移。因此陰囊及陰莖部位柏哲氏疾病的局部復發或遠處轉移,取決於手術切除是否完全及柏哲氏細胞侵犯的深度而定。 對於柏哲氏細胞侵犯至真皮層。且多次復發者,可考慮大範圍局部切除合併化學治療;而對於無法接受手術治療的患者,予以放射治療可能會有幫助。 |
英文摘要 | From 1984 to 1994, seventeen cases of penoscrotal Paget's diseases were treated in VGH-Taipei. Those tumor cells confined to the epidermal layer and free cut margin, no local recurrence or distant metastasis was noted in six cases. On the other hand, four local recurrence and three distant metastasis are noted in nine cases which tumor cells invaded to the dermal layer, even the cut-margin is free of tumor cell. Therefore, local and distant disease control are related to adequate local excision and the depth of tumor invasion. In those tumor cells invaded to dermal layer with repeated local recurrence, wide excision combined with chemotherapy maybe considered, and radiotherapy may have some advantage in those far advaned cases. |
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