查詢結果分析
相關文獻
- Relationship Between Hemodynamics and Plasma Atrial Natriuretic Peptide in Children with Ventricular Septal Defect or Patent Ductus Arteriosus
- Successful Treatment of Patent Ductus Arteriosus in Two Dogs
- The Anesthetic Management of A Preterm Infant Weighing 500 Grams Undergoing Ligation of Patent Ductus Arteriosus--A Case Report
- Renal Effects and Urinary Excretion of Prostaglandin Following Indomethacin Therapy in Premature Infants with Patent Ductus Arteriosus
- Transatrial Repair of Perimembranous Ventricular Septal Defects
- 早產兒的開放性動脈導管
- Prenatal Diagnosis of Complete Transposition of the Great Arteries with Ventricular Septal Defect and Left Ventricular Outflow Tract Obstruction: Report of a Case
- Detachment of Ventricular Septal Defect Patch in Echocardiography--A Case Report
- Risk Factors of Pulmonary Hemorrhage in Very-Low-Birth-Weight Infants: A Two-year Retrospective Study
- Surgical Repair of Postinfarction Ventricular Septal Defect
頁籤選單縮合
題 名 | Relationship Between Hemodynamics and Plasma Atrial Natriuretic Peptide in Children with Ventricular Septal Defect or Patent Ductus Arteriosus=心室中隔缺損或開放性動脈導管之病兒其血行動力學與心房利鈉胜冴之相關性 |
---|---|
作 者 | 戴任恭; 黃德揚; 吳俊仁; 黃旼儀; | 書刊名 | 中華民國小兒科醫學會雜誌 |
卷 期 | 36:2 民84.03-04 |
頁 次 | 頁86-92 |
分類號 | 417.5223 |
關鍵詞 | 心房利鈉胜冴; 心室中隔缺損; 開放性動脈導管; Atrial natriuretic peptide; ANP; Ventricular septal defect; Patent ductus arteriosus; |
語 文 | 英文(English) |
中文摘要 | 爲了探討心房利鈉勝肽(ANP)在右邊中心循環各腔室的濃度與血行動力學之關係,本研究共收集20位患有心室中隔缺損或開放性動脈導管的心臟病兒,利用萃取及核子免疫分析法來定量血漿ANP濃度。結果顯示;ANP的濃度從下腔靜脈(116±18.1pg/ml,mean±SE),右心房(160±21.6pg/ml)到肺動脈 (253.4±38.8pg/ml)逐次上升。在10位心室中隔缺損及10位開放性動脈導管之病兒,其下腔靜脈ANP濃度均分別可與肺體循環血流比(Qp/Qs)(r=0.69,p<0.05;r=0.94,p<0.01)、肺動脈收縮壓(r=0.90,P<0.01;r=0.93,p<0.01),肺動脈舒張壓(r=0.76,p<0.02;r=0.69,p<0.05)和肺動脈平均壓(r=0.88,p<0.01;r= 0.87,P<0.0l)可成正腺性迴歸相關。兩者的肺動脈ANP濃度亦均分別與Qp/Qs成正腺性迴歸相關(r=0.81,p<0.01;r=0.87,p<0.01)。因此,我們結論;具有左至右分流的先天性心臟病,其左心房的體積負荷對ANP在體內的分泌會造成重要影響。 |
英文摘要 | To evaluate the relationship between concentrations of ANP in plasma of the right-sided central circulation and hemodynamic parameters in congenital heart disease with left-to-right shunt, We enrolled 20 children aged from 1 month to 4.8 years with ventricular septal defect (VSD) or patent ductus arteriosus (FDA). The concentrations of ANP in plasma were extracted through a cartridge (Sep-Pak C,8) before being measured by radioimmunoassay. Significant increased concentrations of ANP in plasma from inferior vena cava (117.6±18.1pg/mL), right atrium (160.6±21.6pg/mL) to pulmonary artery (PA) (253.4±38.8pg/mL) were recognized. In VSD (n=10) and FDA (n=10), the concentrations of ANP in plasma from the inferior vena cava correlated significantly with the ratio of pulmonary to systemic blood flow (Qp/Qs) (r=0.69, p<0.05; r=0.94, p<0.0l respectively), the systolic pulmonary artery pressure (r=0.90, p<0.01; r=0.93, p<0.01 respectively), the diastolic pulmonary artery pressure (r=0.76, p<0.02, r=0.68, p<0.05 respectively), and the mean pulmonary artery pressure (r=0.88, p<0.0l; r=0.87, p<0.0l respectively). The concentrations of ANP in plasma from the pulmonary artery also correlated significantly with the Qp/Qs (r<0.81, p<0.0l; r=0.87, p<0.0l respectively). The results indicated that left atrial volume loading may have an important influence on secretion of ANP in some congenital heart disease with left to right shunt. |
本系統中英文摘要資訊取自各篇刊載內容。