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頁籤選單縮合
題 名 | Congenital Malformation in Newborns Analysis of 510 Cases=新生兒先天異常510例經驗 |
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作 者 | 謝燦堂; 羅良明; 徐振傑; 邱宗鴻; 劉瑞德; 謝景璋; 張廷彰; | 書刊名 | 長庚醫學 |
卷 期 | 18:1 1995.03[民84.03] |
頁 次 | 頁14-19 |
分類號 | 417.517 |
關鍵詞 | 先天異常; 產前診斷; Malformation; Anomaly; Prenatal diagnosis; |
語 文 | 英文(English) |
中文摘要 | 長庚醫院在14年44,362例生產中,510個新兒出生時發現有缺陷。我們對母親的年齡、懷孕週數、胎次、嬰兒性別及出生體重做了分析,並與對照組比較。我們發現兩者母親平均年齡及胎次並無明顯差異。但若胎兒具有染色體異常,則其母親平均年齡大於對照組。在懷孕週數方面,胎兒異常者,其懷孕週數較短,但具顱顏異常者除外。此外,在這些異常的胎兒中,有較高比率的胎內生長遲滯。 這些異常系統區分,前三位分別是中樞神經系統、骨骼肌肉系統及顱顏系統。若以疾病來看分別是唇顎裂、無腦症、多指症、胎兒水腫、唐氏症及囊性分腫。 由於超音波設備及其它診斷技術的進步,許多胎兒異常可事先診斷。若其缺陷可以用外科矯正,則可以繼續懷孕,出生後再接受治療,如唇顎裂。至於不適生存的畸型,若在24週以前診斷,則醫師有較大的處理空間。因24週以後就還要考慮到法令規章。因此醫師應努力於胎兒異常的早期診斷。 |
英文摘要 | Over a 14-year period in Chang Gung Memorial Hospital, 510 out of 44, 362 newborns were found to have birth defects. Maternal age, gestational age, parity, infant sex and birth weight were analyzed for each anomaly and compared to normal newborns. The average maternal age and parity for newborns with congenital anomalies were not significantly different from normal newborns. Mothers giving birth to babies with chromosomal aberrations, however, had a significantly older maternal age than the normal population. The gestational age at delivery significantly shorter for all except craniofacial anomaly. In addition, there was a high percentage of incept craniofacial anomaly. In addition, there was a high percentage of intrauterine growth retardation congenital anomalies. The central nervous system, the musculoskeletal system and craniofacial systems were the most commonly involved. The leading anomalies included cleft lip, cleft palate, anencephaly, polydactyly, hydrops fetalis, trisomy 21 and cystic hygroma. With improved ultrasound equipment and other prenatal diagnostic procedures, many defects of the fetus can now be identified. If the fetus is diagnosed with a surgically correctable lesion like cleft lip, it can be kept to term, delivered, then managed postnatally. If life-incompatible malformations have been detected before the 24th week, physicians are in a good position to counsel the parents. After the 24th week termination is proscribed by law. Therefore, physicians must take special care to detect fetal abnormalities early. |
本系統中英文摘要資訊取自各篇刊載內容。