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- 以I-131 MIBG閃爍攝影配合X光電腦斷層攝影評估疑似嗜鉻細胞瘤的高血壓患者
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頁籤選單縮合
題名 | 以I-131 MIBG閃爍攝影配合X光電腦斷層攝影評估疑似嗜鉻細胞瘤的高血壓患者 |
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作者 | 張寶源; 張榮和; 吳澤民; 鄧子雲; 錢本文; 蘇誠道; | 書刊名 | 慈濟醫學 |
卷期 | 6:1 1994.03[民83.03] |
頁次 | 頁41-48 |
分類號 | 414.93 |
關鍵詞 | I-131 MIBG閃爍攝影; 嗜鉻細胞瘤; X光電腦斷層攝影; I-131 MIBG scintigraphy; Pheochromocytoma; X-ray CT; |
語文 | 中文(Chinese) |
中文摘要 | 本回溯性的研究蒐集了33位臨床疑似嗜鉻細胞瘤的高血壓患者,分析其 I-131MIBG閃爍攝影,配合X光電腦斷層攝影(CT),以評估I-131 MIBG診斷此類患 者的情形。12例經手術切除及病理檢查證實為其正病灶,21例經由臨床追蹤或手 術排除嗜鉻細胞瘤或其他能產生catecholamine的腫瘤。12例真正病灶中,7例為為 單側腎上腺嗜鉻細胞瘤,2例為兩側腎上腺嗜鉻細胞瘤,1例為神經節神經性細胞 瘤,1例兩側腎上腺髓質肥厚症,1例為轉移性嗜鉻細胞瘤。MIBG均將這些病灶 顯影,CT則在MIBG的指引下,除了一例腎上腺髓質肥厚症無法確定診斷外,在 相關部位的檢查也將病灶很好的定位。我們認為MIBG檢查是一個敏感度很高的 檢查,除了腎上腺外,也可以偵測異位性的嗜鉻細胞瘤或其他神經內分泌瘤。若 配合CT檢查,則可以很好的替病灶定位。(慈濟醫學1994:6:41-48) |
英文摘要 | In this retropective study, we performed I-131 MIBG scintigraphy and X-ray CT in 33 patients with clinicalsuspicious of pheochromocytoma. 12 cases were proved to have true organic lesion by surgery and pathology, 21 wereruled out through long-term clinical follow-up and operation. Among 12 cases of adrenal medullary lesions, 7 caseswere unilateral adrenal pheochromocytoma, 2 cases were bilateral pheochromocytoma, 1 case was ganglioneuroma,1 cases was bilateral medullary hyperplasia, 1 case was metastatic pheochromocytoma. 1-131 MIBG demonstratedall these lesions. Under guidance of MIBG, CT well localize all lesions except the case of adrenal medullary hyperplasia. We conclude that, I-131 MIBG is a high sensitive modality for detecting catecholamine secreting lesions.Beside adrenal gland, it can also detect ectopic pheochromocytoma or other neuroendocrine tumors. As correlationwith CT scan, it can well localize and more specify the lesions. (Tzu-Chi Med J 1994; 6: 41-48) |
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