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題名 | Alzheimer病並存澱粉樣腦血管病附10例臨床及病理分析 |
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作者姓名(中文) | 徐惠琴; 徐克強; 王耀山; | 書刊名 | 慈濟醫學 |
卷期 | 5:2 1993.06[民82.06] |
頁次 | 頁119-123 |
分類號 | 415.9341 |
關鍵詞 | Alzheimer病; 腦血管病; 澱粉樣; |
語文 | 中文(Chinese) |
中文摘要 | 245例連續腦屍解病例中篩選出10例Alzheimer病並存的澱粉樣腦血管 (CAA)病例,臨床病程0.5~6年,表現不同程度智能障礙,屍解見不同程度的腦萎 縮。CAA病變廣泛累及腦葉皮層和腦膜血管,老年斑(SP)多見於腦葉皮層,而神 經原纖維纏結(NFT)則多見於海馬。臨床表現痴呆嚴重的病例,腦內CAA-SP和NFT 病變亦嚴重。(慈濟醫學1993:5:119-123) |
英文摘要 | In a series of 245 autopsy cases, we selected 10 pathologically verified cases of Aizheimer's disease withcerebral amyloid angiopathy (CAA). Clinical courses vary from 0.5 to 6 years. These patients present someextent of mental retardation. At autopsy, some degree of brain atrophy are found. CAA can invade throughoutcortex and leptomeninges vessels. Senile plaques (SP) often appear in the cortex, but neurofiblillary tangles(NFT) are usually observed in hippocampus. The more severe dementia, the more severe pathologic changessuch as CAA, SP an NFT. (Tz'u-Chi Med J 1993; 5: 119-123) |
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