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頁籤選單縮合
題名 | Bile Duct Proliferation in Cholestatic Liver=膽汁鬱積肝之膽管再生作用 |
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作者 | 陳三多; | 書刊名 | 臺灣畜牧獸醫學會會報 |
卷期 | 60 1992.12[民81.12] |
頁次 | 頁65-73 |
分類號 | 437.24 |
關鍵詞 | 再生作用; 膽汁; 膽管; 鬱積肝; |
語文 | 英文(English) |
中文摘要 | 老鼠膽管結紮手術已被廣泛應用於膽汁鬱積時之形態學或生物化學之研究,然 而,大部份的研究均集中於短時間內引起之病理變化,本研究乃欲觀察膽管經長時間結紮 後,膽道系統之病理變化,當膽管被結紮後,所有的實驗老鼠均呈現急性膽汁鬱積之臨床症 狀,但大部份均於十五天後漸漸恢復正常,甚至回復到正常的狀態,以組織病理切片檢查發 現在肝實質,總膽管壁以及附近的結締組織有許多新生成之膽管,因此推論,膽管之再生作 用可能是老鼠經膽管結紮後仍能存活的原因。 |
英文摘要 | Bile duct ligation in rat had been extensively used in the morphologic or biochemical studies of cholestasis. However, most investigations were concentrated in the pathological changes during a short period. The aim of this study is to observe the patjhological changes of biliary system after a long term common bile duct ligation. While the bile ducts were ligated, all the experimental rats showed the clinical signs of acute cholestasis, but most of them were recovered gradually after day 15, even, returned to normal condition. By histopathological examination, many newly formed bile ducts were found in the liver parenchyma, the wall and the surrounding connective tissue of common bile duct. It was suggested that the proliferation of bile duct is the possible reason for suriving in bile duct ligated rat. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。