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來源資料
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頁籤選單縮合
| 題 名 | Diagnostic Accuracy of Frozen Sections in Surgical Pathology A Retrospective Analysis of 1084 Frozen Sections=外科病理之冷凍切片診斷率之評估回顧1084例冷凍切片診斷之結果分析 |
|---|---|
| 作 者 | 張俊梁; | 書刊名 | 醫學研究 |
| 卷 期 | 13:2 1992.09[民81.09] |
| 頁 次 | 頁133-142 |
| 分類號 | 416.1 |
| 關鍵詞 | 外科病理; 冷凍切片; 診斷率; |
| 語 文 | 英文(English) |
| 中文摘要 | 自1989年10月至1990年10月,三軍總醫院病理部共接受了1084例外科手術中完成送檢標本之冷凍切片檢查,送檢完之標本並經福馬林液固定,腊塊包埋,且經hematoxylin & eosin(H&E)染色處理。本報告依送檢標本之部位分為12類,如乳房部位(282例),胃腸道(172例),甲狀腺(161例),骨骼及軟組織(128例),腦部(89例),淋巴結組織(84例),卵巢(53例),泌尿道(41例),子宮及子宮頸(36例),腮腺(20例),肺部呼吸道(14例),口腔部(4例)。冷凍切片檢查診斷之結果並與最後H&E染色結果相比較,依分析結果分為偽陰、陽性與診斷未定三項。結果顯示,冷凍切片檢查之正確率為97.9%(1059/1084),其中偽陰性率為1.3%(14例),偽陽性率為0.4%(4例),診斷未定者為0.6%(7例)。冷凍切片檢查於良性腫瘤之正確診斷率為99.4%(708/712),其中偽陽性者為0.6%(4例);而屬惡性腫瘤之正確診斷率為94.3%(351/372),其中偽陰性為3.8%(14例),診斷未定者為1.8%(7例)。依本文研究之結果顯示,冷凍切片檢查之正確診斷率高低依序為泌尿道系統,子宮及子宮頸,腦部組織及肺部,乳房部位,胃腸道,卵巢,甲狀腺,淋巴系統,骨骼與軟組織,腮腺和口腔部。綜合本研究結果與過去文獻所報告之結果相比較,吾等認為冷凍切片檢查具有高度之正確診斷率,且可提供外科醫師於外科手術中之快速診斷,並決定對病患是否更進一步治療之需要;於外科病理醫師而言,可提供自我品質管制度及住院醫師之教學訓練計劃。 |
| 英文摘要 | One thousand and eighty-four consecutive intra-operative frozen sections consultations performed during a 1-year period were evaluated retrospectively, in order to assess the accuracy of the method and develop a quality control system. The frozen sections diagnosis was then compared to that found on paraffin permanent H&E sections, the results was categorized into 12 regions in the intra-operative surgical specimen. We found an overall accuracy rate of 97.7%. The total percentage of false negative, false positive and deferred diagnosis were 1.3% (14 cases), 0.45 (4 cases), and 0.65 (7 cases) respectively. Frozen sections diagnosis was most accurate on the benign lesion (99.4%, 708/712 cases) excluded the tissue recognition and malignant lesion was 94.3% (351/372 cases). Areas in which frozen sections diagnosis were least accurate included the bone and soft tissue (94.5%), lymph nodes (96.4%), parotid gland (90%), oral tissues (75%). We therefore concluded that frozen sections diagnosis was highly accurate in the intra-operative pathological service to be accepted as an integral part of the proper management of the surgical patient. |
本系統中英文摘要資訊取自各篇刊載內容。