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題名 | Influence of Maturation on Diastolic Events of Left Ventricle in Children=小兒成熟過程對左心室舒張期變化的影響 |
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作者姓名(中文) | 吳美環; | 書刊名 | 中華民國小兒科醫學會雜誌 |
卷期 | 33:1 民81.01-02 |
頁次 | 頁35-43 |
分類號 | 417.5212 |
關鍵詞 | 小兒; 左心室; 成熟; 舒張期; 過程; 影響; 變化; |
語文 | 英文(English) |
中文摘要 | 我們對120例正常先施行心臓超音波檢查並測定其舒張期的變化,藉以了解心臓舒張期變化於成熟過程的演變。等容心舒張期(isovolumic relaxation period)係指由主動脈瓣關閉的時間至二尖瓣開啓時的間距,在各年齡層並無明顯差異;然而等容心舒張期長度可分別在嬰兒、兒童或青少年期,以不同的線性關係,由心跳週期長度預估。在整個受檢群,心舒張充血期(total diastolic period, DTP),則不分年齡層,可由心跳週期長度(CL)依下列線性公式來預測其長度,DTP=0.58×CL-75.2(r=0.89, p<0.001)。早期心舒張充血期(early diastolic filling, D-F),和心舒張充血期相似,在所有年齡層的受檢者,早期心舒張充血期和心舒張充血期長度有明顯的線性相關;D-F=0.57×DTP+0.11(r=0.93, p<0.001)。至於早期心舒張血速度心房張充血的速度比,隨著年齡的增加,由於早期心舒張充血速度逐漸增加,而有漸增的趨勢。我們由以上結果推論,各種不同心舒張期變化在成熟過程中的演變並不一致。主要反映其心肌舒張性與心負荷量(load)的成熟演變與程度不一的影響造成的總結果。 |
英文摘要 | To delineate the influence of maturation process on diastolic events of cardiac cycle, we had performed M-mode and Doppler echocardiography in 120 normal subjects aged from 1 hour to 16 years. The isovolumic relaxation period (IVRP, msec), defined as the time interval between the aortic valve closure to the mitral valve opening, was not statistically different in various age groups. Different equations based on individual ranges of cycle length (CL) were disclosed for each of three different age groups, demonstrating a positive linear correlation between IVRP and CL. On the contrary, an equation showing a linear correlation between diastolic total period (DTP, msec) and CL could be applied to all age groups: DTP=0.58×CL-75.2 (r=0.89, p<0.001). Similarly applicable to all age groups, the duration of early diastolic filling (D-F, msec) changed with DTP in all age groups by an equation: D-F=0.57×DTP+0.11 (r=0.93, p<0.001). Ratios between the maximal velocity of early (E) and atrial (A) diastolic filling increased gradually with age. This was largely due to an increase in E with maturation, suggesting a depressed early diastolic filling in the young hearts. We conclude that the patterns of diastolic relaxation and filling are heterogeneously affected by the degree of maturation and represent the net results of complex interactions between changing inactivation properties and loading status at various stages. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。