查詢結果分析
來源資料
相關文獻
- 鍺﹣﹣四 (甲基) 波菲林衍生物之合成
- Synthesis of Germanium Tetra (chloro, p-carboxyphenyl and benzyl) porphyrin Derivatives
- 鍺波菲林衍生物之合成
- 雜環醌類之生理活性(II): 6-胺基-7-氯基-5,8-喹啉醌衍生物之合成及抗生活性
- 有機鍺衍生物之合成與藥效之探討
- Synthesis and Testing of Naphthol Derivatives as Antimicrobial Agents
- α-酮基酸衍生物的合成方法現況
- Azuleno[6,5-d]thiazole Derivatives.I. Synthesis of 2-Benzamidoazuleno[6,5-d]thiazole and Its 6-Methoxy Derivative
- Reaction of Certain Thiosemicarbazides with Bielectrophiles: Synthesis of Some Novel Phthalazinones Containing Thiazolidine Moiety
- Syntheses of 1,2-O-Alkylidene-5- alkyl-5-deoxy- [feb6]-D-xylofuranoses Using as Chiral Auxiliary
頁籤選單縮合
題名 | 鍺﹣﹣四 (甲基) 波菲林衍生物之合成=SYNTHESIS OF GERMANIUM TETRAMETHYL PORPHYRINS |
---|---|
作者 | 姜宏哲; |
期刊 | 師大學報 |
出版日期 | 19900600 |
卷期 | 35 1990.06[民79.06] |
頁次 | 頁217-227 |
分類號 | 418.41 |
語文 | chi |
關鍵詞 | 四甲基波菲林; 合成; 衍生物; 鍺; |
中文摘要 | 一些波菲林、金屬波菲林及有機鍺化合物顯示抗癌作用。因此本研究合成了5種新的鍺-四(甲基)波菲林衍生物(2~6),期能在抗癌療效上有幫助。 四(甲基)波菲林(1)是由?咯和乙醛反應環成。1與四氯化鍺反應,得二氯一鍺一四(甲基)波菲林(2)。將2與礬土搖振得二羥基一鍺一四(甲基)波菲林 (3);與溴化乙基鎂反應得二乙基一鍺一四(甲基)波菲林(4);與溴化苯基鎂反應得到二苯基一鍺一四(甲基)波菲林(5)。由3與對一硝基酚反應得二一(對硝基酚基)者一四(甲基)波菲林(6)。 |
英文摘要 | Some porphyoins, metaloporphyrins and orgnogermanium compounds have antitumor ef-fects. In this study five new germanium tetramethyl porphyrins (2-6) were synthesized. Tetramethyl porphyrin (1) is prepared from pyrrole and acetaldehyde. 1 is reacted with germanium tetrachloride give dichlorogermanium tetramethyl porphyrin (1). Hydrolysis of 2 with alumina give dihydroxy germanium tetramethyl porphrin(3). Reaction of 2 with ethylmag-nesium bromide give diethylgermanium tetramethyl prophyrin(4); reaction with phenylgerma-nium bromide give diphenylgermanium tetramethyl porphyrin(5). Treatment of 3 with 4-nitrophenol give di-(4-nitrophenoxy) germanium tetramethyl porphyrin (6). |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。