頁籤選單縮合
| 題 名 | Use of parasympatholytics=副交感神經抑制劑之使用 |
|---|---|
| 作 者 | Berdel,D.; Berg,A. V.; | 書刊名 | 中華民國小兒科醫學會雜誌 |
| 卷 期 | 30:6 民78.11-12 |
| 頁 次 | 頁378-388 |
| 分類號 | 418.217 |
| 關鍵詞 | 副交感神經抑制劑; |
| 語 文 | 英文(English) |
| 英文摘要 | The role of the vagus in bronchial asthma implicates to suggest that parasympatholytics are potent drugs in asthma therapy. The most important parasympatholytics today are ipratropium and oxitropium bromide. They are effective by blocking the cholinergic or muscarinic receptors of the bronchial smooth muscle and thereby inhibit cholinergic bronchomotor tone. Although they are generally somewhat less effective bronchodilators compared to β2-adrenergics, they are potent antiasthmatic drugs especially in infants and small children, in whom β2-adrenergics seem to be not so much effective. As with inhaled β2-adrenergics a correct inhalation technique is required for an optimal effect with parasympatholytics as well, but it could be shown that both groups of substances do have a good antiobstructive effect even when just sprayed into the mouth. Apart from the theoretical implications discussed the clinical importance of these findings for the antiobstructive treatment of those patients unable to inhale properly including infants and small children is emphasized. |
本系統中英文摘要資訊取自各篇刊載內容。