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頁籤選單縮合
題名 | Comparison of Oocyte Morphology with Serum and Follicular Fluid FSH, LH, PRL and E[feaf]in Women Undergoing in Vitro Fertilization=接受體外受孕婦女的血清及卵泡液中之性激素濃度與卵子成熟度之比較 |
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作者 | 師明哲; | 書刊名 | 醫學研究 |
卷期 | 8:6 1988.05[民77.05] |
頁次 | 頁367-375 |
分類號 | 417.12 |
關鍵詞 | 比較; 成熟; 血清; 卵子; 卵泡液; 受孕; 性激素; 婦女; 接受; 濃度; 體外; |
語文 | 英文(English) |
中文摘要 | 測量接受本院體外受孕計劃有的七十九位病人血清中及卵泡液中之卵泡促進激素,黃體促進激素、催乳素和雌二醇濃度。七十九位病人共押取三○七個卵泡,發現二二五個卵子,其中一六六個卵子受孕成功,一二五個分裂,有八位病人顯示生化妊娠,二位病人成功妊娠及生產。卵子的成熟度依觀察分四組,依次為縮、不成熟、成熟第一級,和成熟二級,分析卵子的成熟度和血清中及卵泡液中激素濃度比較,其中血清及卵泡液中激素濃度越高者,卵子越成熟,同時合併之不成熟卵也愈多。血清及卵泡液中之雌二醇值呈現與卵子成熟、受孕、分裂及妊娠相當有關。而卵泡促進激素可增加雌二醇之產生,然催乳素及黃體促進激素則不然。 |
英文摘要 | The Serum and follicular fluid concentrations of Follicle Stimulating Hormone (FSH), luteinizing Hormone (LH), Prolactine (PRL) and Estradiol (E2) were measured in 79 cases undergoing In-Vitron Fertilization (IVF). In our hospital-based IVF program, 307 follicles were followed, 225 eggs recovered, 166 eggs fertilized, 125 eggs cleft, and 8 biochemical pregnancies and 2 full term babies were achieved. The maturity levels of the oocytes were divided into 4 groups: immature, mature (stage I), mature (stage II), and atretic. The morphology and maturity of the oocytes were analyzed and compared with the hormone levels is serum and follicular fluid. More mature oocytes were produced with higher levels of FSH, LH, PRL and E2 in serum and follicular fluid. At the same time, more immature occytes were produced as well. (FSH: r=0.78, p<0.01; LH:R=0.53, P<0.01; PRL:R=0.53, P<0.01). The estradiol levels in both serum and follicular fluid showed good correlation with oocyte maturity, fertility, cleavage and with pregnancy rate (p<0.01). FSH enriched follicular E2 production (R=0.69, P<0.01), and the releasing of FSH were accompanied by a marked increase of circulating E2, whereas similar responses were not observed with varying levels of PRL and LH. |
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