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| 題 名 | The Clinical and Laboratory Evaluation of Acute Paralytic Poliomyelitis=急性小兒麻痺症在臨床及實驗室上的評估 |
|---|---|
| 作 者 | 湯仁彬; | 書刊名 | 醫學研究 |
| 卷 期 | 8:4 1988.01[民77.01] |
| 頁 次 | 頁219-226 |
| 分類號 | 415.93152 |
| 關鍵詞 | 急性小兒麻痺症; |
| 語 文 | 英文(English) |
| 中文摘要 | 1982年夏季,小兒麻痺在臺灣肆虐,48例疑似小兒麻痺病童曾就診榮民總醫院,其中40例經病毒培養及血清抗體證實為第一型小兒麻痺病毒所引起。33例經培養證實有第一型小兒麻痺病毒,其中15例單獨由糞便(或肛門拭子),7例單獨由咽喉拭液獲得,11例由咽喉拭液及糞便中培養出該病毒。血清之中和性抗體在急性發作時略已升高,在未培養出病毒的其他病例中,有4例之急性與恢復期血清中和抗體呈現四倍或四倍以上增加,另有3例之恢復期血清呈現高效價抗體,顯示最近有該病毒的感染。最明顯的臨床症狀為發燒及下肢肢體麻痺,腦脊髓液檢查多呈現細胞數目增加,蛋白正常或微升,糖份正常。 |
| 英文摘要 | An outbreak of paralytic poliomyelitis occurred in Taiwan during the summer of 1982 when 48 cases were admitted to Veterans General Hospital, Taipei. The laboratory and clinical findings of these cases were described. Forty of 48 cases were confirmed to be type 1 poliomyelitis, and type 1 poliovirus was isolated from 33 patients. Fifteen patients had virus isolated from anal-fecal swabs alone, 7 patients had isolation of virus form throat swabs alone and, in 11 patients, both anal-fecal and throat swabs had positive poliovirus isolation. The neutralizing antibodies rapidly rose after onset of clinical findings. Of the remaining seven cases, there was a fourfold rise of neutralizing type 1 antibody in four, and a high titer of neutralizing antibody in the single serum samples in three. The most predominant clinical finding was fever; the most common motor disability involvement was in the lower limbs. Examinations of cerebrospinal fluid showed pleocytosis with normal or slight elevation of protein, and a normal level of glucose. |
本系統中英文摘要資訊取自各篇刊載內容。