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| 題 名 | Comparative Efficacy of Piroxicam, Indomethacin and Placebo-controlled in the Treatment of Osteoarthritis=Piroxicam, indomethacin 及安慰劑對治療退化性關節炎的藥效比較 |
|---|---|
| 作 者 | 陳進祥; | 書刊名 | 醫學研究 |
| 卷 期 | 8:2 1987.09[民76.09] |
| 頁 次 | 頁93-98 |
| 分類號 | 415.952 |
| 關鍵詞 | 比較; 安慰劑; 治療; 退化性; 藥效; 關節炎; |
| 語 文 | 英文(English) |
| 中文摘要 | 多數的非類固醇抗炎藥是有效的抗炎上痛劑。在本項為時6週,98位病人的研究中,由醫師與病人共同評估多項piroxicam與indometh對膝或股退化性關節炎的療效。結果顯示,兩種非類固醇抗炎藥對治療退化性關節炎具有相同的藥效,研究並發現piroxicam與indomethacin對關節功能的改善,在統計學上顯然有意義於優於安慰濟,在腸胃道方面,病人對piroxicam的耐受性,在統計上較indomethacin為佳。 |
| 英文摘要 | In this six-week study, multiple categories were designed to discern the clinical efficacy of piroxicam (15mg orally once daily) and indomethacin (25mg orally four times a day) in treatment of 98 patients with osteoarthritis (O.A.) of the knee and/or hip. Based on evaluations by both physicians and patients, there were no statistically significant difference between the two NSAIDs-treated groups in most of the efficacy parameter studied (all p>0.001). This study also indicated that both prioxicam and indomethacin were superior to placebo in the treatment of O.A. (all p<0.001). In accord with the gastrointestinal tract, the piroicam-treated subjects had significant lower incidence of digestive problem compared with the indomethacin group (p<0.001). |
本系統中英文摘要資訊取自各篇刊載內容。