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題名 | 國人大腸直腸癌發生於40歲前或後之比較 |
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作者 | 鄭智勇; | 書刊名 | 醫學研究 |
卷期 | 6:4 1986.06[民75.06] |
頁次 | 頁317-325 |
分類號 | 415.569 |
關鍵詞 | 40歲; 大腸直腸癌; |
語文 | 中文(Chinese) |
中文摘要 | 年輕人之大腸癌較為少見,尤其是發生於20歲以下者,其預後之評估,更是論調不一,有著很大的出入。自1956年1月至1985年10月的30年間,三軍總醫院共有647例大腸直腸癌患者。其中小於40歲者(包括40歲),計有89位,約佔全部病例的13.8%。若與大於40歲病例相比,除癌瘤發生於乙狀結腸處較少外,其他解剖位置上的分佈比例是類同地。值得注意的是,黏液癌和指環狀細胞癌佔全部病例的25.8%,比大於40歲患者之3.4%要高出甚多。其次,89位患者中有46位(52%)是C₂侵犯期,而大於40歲患者有34.4%(192/558)是屬於C₂侵犯期。在追踪的26例小於40歲患者,C侵犯期加上D侵犯期共為14位,佔全部追踪者的54%(14/26),而大於40歲患者是42%(46/110)。顯示年輕患者的診斷時間較為延遲。小於40歲患者之癌瘤比大於40歲者含較豐富的0-乙醯涎黏液,但硫黏液與涎黏液之比例,二者之間無明顯差異.小於40歲患者的5年存活率是38.5%,與大於40歲患者之38.2%相比,幾無差異。然而,高比例的黏液癌和晚期診斷是造成年輕患者較多晚期癌瘤的因素。 |
英文摘要 | Colorectal cancer in young people is uncommon, especially in the group under twenty years old. Prognosis of young age group patient was debated in many previous and recent reports. From 1956 to 1985, 647 patients were diagnosed as colorectal carcinoma in T.S.G.H. Eightynine of them were under 40 years (including 40) of age and represented 13.8% of all colorectal carcinoma during the same study period. In compare with old age group (>40 years old), the young patients have some criteria as following: (1) Lower frequency of occurrence of tumors, located in sigmoid colon. (2) Higher ratio of mucinous carcinoma and signet-ring cell carcinoma (25.8% vs. 3.4% of the old age group). (3) More aggressive invasion of tumor stage. However, the overall five year survival rate of the young age group was 38.5%, not worse than that of the old age group. Early diagnosis and treatment are very important in young age patients. Histochemistry and pathological findings of colorectal carcinoma were also studied in this article, and wave also compared with that of the old age group. |
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