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題 名 | 血液癌症及其他疾病骨髓與末稍血液中免疫球蛋白量之比較 |
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作 者 | 鍾來如; | 書刊名 | 醫學研究 |
卷 期 | 4:3 1982.01[民71.01] |
頁 次 | 頁1297-1302 |
分類號 | 415.6 |
關鍵詞 | 末稍血液; 血液癌症; 免疫球蛋白量; 骨髓; |
語 文 | 中文(Chinese) |
中文摘要 | 多發性骨髓瘤及淋巴球增殖症之骨髓中各種漿細胞、淋巴球可製造免疫球蛋白。為了瞭解骨髓中免疫球蛋白量是否與末梢血中者有差異,乃以33例各種血液癌症及其他疾病患者為對象,從事骨髓細胞形態檢查,骨髓抽出液及末梢血中免疫球蛋白量之測定。結果顯示多發性骨髓瘤(IgG)及巨球蛋白血症(IgM)兩者骨髓及末梢血中免疫球蛋白量成一直線關係,其相關係數,r=0.98而其f值為0.0116,p值為0.9161,表示此兩種體液中之免疫球蛋白數值無統計學上之顯著差異。其他血液疾病骨髓及末梢血中免疫球蛋白量關係亦復如此。再者,骨髓內漿細胞或淋巴球之多寡不一定能反映其免疫球蛋白高低,r=0.66,尤其巨球蛋白血症患者,其骨髓內漿細胞或淋巴球數目可在正常值內。 |
英文摘要 | Large amounts of immunoglobulin are produced by various plasma cells in the bone marrow, as in patients with multiple myeloma and lymphopro-liferative disorders. Whether the immunoglobulin level is different between the bone marrow and peripheral blood or not, it remains unclear. A study of immunoglobulin levels in 33 patients suffering from hematologic malignancies and other disorders was carried out. In these cases, morphological identification of the bone marrow cells was determined. The results were obtained as follows: the immunoglobulin levels in bone marrow and peripheral blood in multiple myeloma (IgG) and macroglobulinemia (IgM), there was a strong correlation, the correlation coefficient r=0.98, whereas f=0.0116, p=0.9161. Thus, no statistical difference was noted. In other diseases including lymphomas, leukemias and various anemias the same results were shown. It is also noted that the percentage of plasma cells or lymphoid cells in the bone marrow does not necessarily reflect the levels of immunoglobulin in it, r=0.66, especially in case of macroglobulinemia in which the bone marrow picture may show non-diagnostic. |
本系統中英文摘要資訊取自各篇刊載內容。