查詢結果分析
相關文獻
- 前降鈣素應用於敗血症診斷與抗生素管制
- 新生兒細菌性敗血症
- 新生兒細菌性敗血症
- 新生兒細菌性敗血症
- 一例草魚細菌性敗血症的診治體會
- 前降鈣素(Procalcitonin, PCT):一個使用抗生素的指南
- 前降鈣素原與發炎指標對菌血症預測準確度之比較
- 對於新生兒疑似早發性敗血症使用前降鈣素作為縮短抗生素治療的指引:前瞻性隨機介入性試驗
- Procalcitonin May be a Potential Biomarker for Distinguishing Bacterial Infection from Disease Activity in Febrile Patients with Systemic Lupus Erythematosus
- 敗血病的診斷指標--前降鈣素PCT(Procalcitonin)
頁籤選單縮合
| 題 名 | 前降鈣素應用於敗血症診斷與抗生素管制=Procalcitonin for Diagnosis of Sepsis and Decisions of Antibiotic Use |
|---|---|
| 作 者 | 陳星宇; 楊雅頌; 孫俊仁; | 書刊名 | Journal of Biomedical & Laboratory Sciences |
| 卷 期 | 25:2 2013.06[民102.06] |
| 頁 次 | 頁39-44 |
| 分類號 | 415.12 |
| 關鍵詞 | 細菌性敗血症; 前降鈣素; 抗生素管制; Bacterial sepsis; Procalcitonin; Antibiotic stewardship; |
| 語 文 | 中文(Chinese) |
| 中文摘要 | 細菌性敗血症與病人的罹病率與死亡率有直接關係。血液培養是診斷血流感染的標準方法,但是受限於無法即時提供檢驗結果。因而造成病人經常性暴露於不需要且長期的抗生素治療,不適當的抗生素治療也增加了抗藥性細菌的篩選。前降鈣素(Procalcitonin; PCT)是一個針對包含敗血症在內的細菌感染症具有早期且正確診斷的指標。根據之前隨機控制實驗結論也提及使用前降鈣素數值作為評估是否開始或停止使用抗生素治療的益處。但是,臨床檢驗必須注意前降鈣素診斷準則及其可能產生偽陽性與偽陰性的問題。這綜論主要目標為提供前降鈣素應用於診斷細菌性敗血症的概論與抗生素使用依據與否的依據。 |
| 英文摘要 | Bacterial sepsis is associated with morbidity and mortality among populations worldwide. Blood culture remains the gold standard in the diagnosis of bloodstream infections, but it has clear limits of rapidity and sensitivity. However, unnecessary and prolonged exposure to antibiotic agents adversely affects patient outcomes, while inappropriate antibiotic therapy increases selection of antibiotic resistant bacteria. Procalcitonin (PCT) is an early and accurate diagnostic biomarker of bacterial infections, including sepsis. Previous conclusions of randomized controlled trials have also shown a benefit of using PCT algorithms to guide decisions about initiation and discontinuation of antibiotic therapy. However, Clinical usage of PCT must appreciate the complexity of diagnostic algorithms for sepsis and limitations of PCT include false-positive and false-negative results. This review aims to provide an overview of the potential of procalcitonin to guide diagnosis of bacterial sepsis and guide to antibiotic decisions. |
本系統中英文摘要資訊取自各篇刊載內容。