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| 題 名 | Comparisons of Early Intervention of NIV between Patients with Acute Respiratory Failure Diagnosed as Pneumonia and Chronic Obstructive Pulmonary Disease=早期介入非侵襲性呼吸器對肺炎與慢性阻塞性肺疾病呼吸衰竭患者療效之比較 |
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| 作 者 | 邱繼云; 顏鴻章; | 書刊名 | 台灣急重症醫學雜誌 |
| 卷 期 | 10:3 2025.09[民114.09] |
| 頁 次 | 頁87-94 |
| 分類號 | 415.47 |
| 關鍵詞 | 非侵襲性呼吸器; 急性呼吸衰竭; 急診; Noninvasive ventilation; Acute respiratory failure; Emergency department; |
| 語 文 | 英文(English) |
| 中文摘要 | 背景:非侵襲性呼吸器被倡議可使用於多種成因之急性呼吸衰竭。現今,急診 頻繁使用非侵襲性呼吸器協助肺炎病患,但證實其療效的資料仍有限。本研究目 標為比較早期介入非侵襲性呼吸器對肺炎與慢性阻塞性肺疾病呼吸衰竭患者之療 效。 方法:納入急性呼吸衰竭病因為肺炎與慢性阻塞性肺疾病且於急診早期介入非 侵襲性呼吸器之患者。於早期介入非侵襲性呼吸器後評估結果含死亡率、插管率、 住院天數與非侵襲性呼吸器使用時間。 結果:比較肺炎與慢性阻塞性肺疾病患者之院內死亡率(39% vs. 28.6%, p = 0.468)、插管率(5.1% vs. 7.1%, p = 1)以及非侵襲性呼吸器使用時間(13.1 ± 13.5 days vs. 18.2 ± 13.4 days, p = 0.317)均無顯著差異。此外,與慢性阻塞性肺 疾病相比,早期介入非侵襲性呼吸器之肺炎患者傾向於有更短的住院天數(23.9 ± 12.7 days vs. 31.9 ± 19.9 days, p = 0.144)。 結論:肺炎與慢性阻塞性肺疾病患者於急診早期介入非侵襲性呼吸器,其院內 死亡率、插管率和非侵襲性呼吸器使用時間之療效相似。此外,本研究顯示與慢 性阻塞性肺疾病患者相比,肺炎呼吸衰竭患者傾向於有更短的住院天數。 |
| 英文摘要 | Background: Noninvasive ventilation (NIV) is commonly used for patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Moreover, NIV is administered more frequently to help patients with pneumonia in the Emergency Department (ED) currently, but data to confirm its efficacy are limited. In this study, we aimed to evaluate the effectiveness of NIV in patients with Acute Respiratory Failure (ARF) with pneumonia and chronic obstructive pulmonary disease (COPD). Methods: Patients with ARF diagnosed with pneumonia and COPD were enrolled and treated for early NIV in the ED. Clinical characteristics including age, sex, and illness severity, were recorded. After early NIV intervention, we assessed outcomes, including mortality, intubation rate, length of hospital stay, and duration of NIV. Results: In patients with pneumonia, no significant differences were found in in- hospital mortality (39% vs. 28.6%, p = 0.468), intubation rate (5.1% vs. 7.1%, p = 1), and NIV duration (13.1 ± 13.5 days vs. 18.2 ± 13.4 days, p = 0.317) compared with those with COPD. Moreover, we found a tendency for shorter length of hospital stay in patients with pneumonia compared with that in patients with COPD (23.9 ± 12.7 days vs. 31.9 ± 19.9 days, p = 0.144) after NIV use. Conclusion: Following early NIV intervention in the ED, ARF patients with pneumonia experienced effects similar to those in patients with COPD. In addition, patients with pneumonia tended to have shorter hospital stays than those with COPD. |
本系統中英文摘要資訊取自各篇刊載內容。