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頁籤選單縮合
| 題 名 | 非酒精性脂肪肝、非酒精性脂肪胰與糖尿病的交互作用及處置=The Interplay among NAFLD, NAFPD and Diabetes and Their Management |
|---|---|
| 作 者 | 王景淵; | 書刊名 | 臺灣醫學 |
| 卷 期 | 30:1 2026.01[民115.01] |
| 頁 次 | 頁72-78 |
| 專 輯 | 雙重異位脂肪:從肝臟到胰臟的代謝風暴 |
| 分類號 | 415.54 |
| 關鍵詞 | 非酒精性脂肪胰臟疾病; 異位脂肪堆積; 代謝症候群; 胰島素阻抗; 第2型糖尿病; Non-alcoholic fatty pancreas disease; NAFPD; Ectopic fatty infiltration; Metabolic syndrome; Insulin resistance; Type 2 diabetes mellitus; |
| 語 文 | 中文(Chinese) |
| DOI | 10.6320/FJM.202601_30(1).0009 |
| 英文摘要 | Non-alcoholic fatty pancreas disease (NAFPD) represents a form of ectopic fat accumulation and is frequently comorbid with obesity, metabolic syndrome, type 2 diabetes mellitus (T2DM), and non-alcoholic fatty liver disease (NAFLD). Excessive deposition of fatty acids in the pancreas can trigger chronic inflammation, insulin resistance, and ȕ-cell dysfunction, thereby contributing to the progression of diabetes and potentially pancreatic cancer. The prevalence of NAFPD is increasing globally and is closely associated with age, abdominal obesity, NAFLD, and other metabolic derangements. Advances in imaging modalities have facilitated earlier detection of pancreatic steatosis. Emerging evidence suggests that GLP-1 receptor agonists and SGLT2 inhibitors may ameliorate pancreatic fat accumulation and improve metabolic function, indicating therapeutic potential. Lifestyle interventions such as weight control, physical activity, and dietary modifications also play a preventive role. NAFPD is not only a marker of metabolic disease but may also act as a key driver of disease progression. Future research should focus on the development of non-invasive diagnostic tools, early risk prediction models, and personalized treatment strategies to mitigate the health burden of NAFPD and improve clinical outcomes. |
本系統中英文摘要資訊取自各篇刊載內容。